Lecture 14 Neoplasia III Flashcards

1
Q

What causes hereditary non-polyposis cancer?

A

Defeccts in mismatch repair.

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2
Q

How is Ras normally regulated ?

A

Has exchangeable GTP.

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3
Q

What is Gleevec?

A

Abl inhibitor - very useful in Bcr-Abl mutations.

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