Lecture 14 Flashcards
What is hyperglicemia?
Excess in blood glucose
What does diabetes cause?
Increased thirst, headaches, blurred vision, trouble concentrating, urination
What did Dr. Frederick Banting find in his study?
A successful way to isolate insulin from pancreatic cells in dogs.
What causes glucose blood level to be controlled?
hormone of glucose
What causes Type 1 diabetes?
Insufficient blood insulin caused by viral infections like rotavirus and measles and genetics
How was insulin mass produced?
Through recomb bacteria where insulin genes were inserted for bacteria to transcribe and translate into insulin
How was insulin sequenced?
Using DNA sequencing by Frederick Sanger
How was insulin 3D structure solved?
By Dorothy Hodgkin in 1969 by x-ray crystalagraphy
What is the goal of the Open Insulin?
Produce insulin for those who need it
