Lecture 13: Vision Flashcards
Light
Photons; both energy waves and particles
Layers of the Retina
Ganglion cells, amicrine cells, bipolar cells, horizontal cells, and photoreceptors (rods and cones)
Retinal Ganglion Cells (RGCs)
Sends information to the brain
Amacrine and Horizontal Cells
Lateral interactions (inhibitions) within the retina
Bipolar Cells
Carry information from photoreceptors to the retinal ganglion cells
Photoreceptors
Rods and cones; transduce light signals
Phototransduction
- Occurs in the photoreceptors
- Light strikes a light-absorbing pigment molecule (rhodopsin) in the disc of a photoreceptor
- Rhodopsin breaks into retinal and opsin
- Opsin closes Na+ gates, hyper-polarizing the photoreceptor
- Stops glutamate release
Rods vs. Cones
- Rods are highly sensitive to light- ideal for vision in dim environments
- Rods have a similar response across wavelength (see in black and white)
- Cones are not sensitive, needs more light to be activated
- Cones come in three types, each sensitive to either red, green, or blue wavelengths
Color Blindness
A lack in one or more of the cone pigments results in color blindness
Honeybee Vision
- Humans and bees are both trichromatic, but bees see more ultraviolet light and less red light compared to us
Fovea
- Sharpest vision, corresponds to center of gaze
- Non-photoreceptor cells are pushed aside in the fovea
- High density of cones, few rods
- Therefore, our focus of gaze is optimized for day
- At night, we are nearly blind in the fovea
Receptive Fields of Retinal Ganglion Cells
- Light cause photoreceptor to release less glutamate
- This excites bipolar cells, causing them to release more glutamate*
- Excited bipolar cells excite RGCs
- These RGCs are excited by light at center –> “on-center cells”
- APs are fired
- Another class of bipolar cells is inhibited and inhibited RGCs. These RGCs are “off-center cells” because they are inhibited by light, AP rate is reduced in this case
Lateral Inhibition
Capacity of an excited neuron to reduce the activity of its neighbors
On-center off-surround
- Light in center excites
- No light in periphery excites