Lecture 12 - Control of cardiac output Flashcards

1
Q

What is cardiac output?

A

The volume of blood ejected by each ventricle per minute

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2
Q

What is heart rate?

A

Number of heart beats per minute

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3
Q

What is stroke volume?

A

The volume of blood ejected by each ventricle per beat

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4
Q

What is the formula for cardiac output?

A

Cardiac output = heart rate x stroke volume

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5
Q

What are some factors that affect heart rate?

A

Atrial reflex
Hormones
Venous returnW

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6
Q

What are some factors affecting stroke volume?

A

Filling time
Autonomic innervation
Hormones
Vascular tone

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7
Q

What are chronotropic effects?

A

Factors that affect the heart rate

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8
Q

What is the process of the innervation of the heart?

A

Sensory cells detect a change needs to be made and a signal is sent to the medulla oblongata in cardioregulatory centre

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9
Q

What are the two centres within the cardioregulatory centre?

A

Cardioinhibitory and cardioregulatory centre

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10
Q

Where are chemoreceptors?

A

In the carotid artery and medulla oblongataW

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11
Q

Where are baroreceptors?

A

In carotid artery and aorta

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12
Q

What do chemoreceptors detect?

A

CO2
pH

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13
Q

What do baroreceptors detect?

A

Pressure

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14
Q

What type of chronotropic effect does parasympathetic have?

A

Negative
Lowers heart rate
Reduces CO

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15
Q

What type of chronotropic effect does sympathetic have?

A

Positive
Increases heart rate
Increases cardiac output

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16
Q

What does the parasympathetic division do in control of pacemaker cells?

A

Opens potassium ion channels
Causes faster repolarization

17
Q

What is venous return?

A

Stretches the pacemaker cells which increases heart rate

18
Q

What is the formula for stroke volume?

A

End diastolic volume - end systolic volume

19
Q

What is preload?

A

The degree to which ventricular muscle cells are stretched at the end of diastole
Directly proportional to end diastolic volume
Dependent on ventricular filling time

20
Q

What is contractility?

A

The force produced by ventricular muscle cells during systole at a given period
Has chronotropic and inotropic effects

21
Q

What is afterload?

A

The force the ventricle needs to overcome to open the semilunar valve and eject blood

22
Q

What division are positive inotropic effects?

A

Sympathetic

23
Q

What division are negative inotropic effects?

A

Parasympathetic

24
Q

What are some factors affecting venous return?

A

Posture - blood pools in legs, decreases venous return
Skeletal muscle pump - movement of skeletal muscle constricts veins, increases VR
Respiratory pump - increases venous return

25
Q

What do vaso dilation and constriction do in relation to afterload?

A

Dilation = reduces afterload
Constriction = increases afterload

26
Q

What does sympathetic division do in control of pacemaker?

A

Opens sodium ion channels
Causes depolarisation