Lecture 10 - Haematology 10 Flashcards
How are WBC formed?
Haematopoiesis
What are the five types of WBC?
Neutrophils
Lymphocytes
Eosinophils
Basophils
Monocytes
Which WBC are agranulocytes?
Monocytes
Lymphocytes
Which WBC are granulocytes?
Neutrophils
Eosinophils
Basophils
What are all the types of WBC in order of proportion?
Never
Let
Monkeys
Eat
Bananas
What are the functions of WBC?
Defence against pathogens
Toxin and waste removal
Remove damaged cells
What are some characteristics of WBC?
Can migrate out of the blood stream
Capable of amoeboid movement
Attracted to specific chemical stimuli
What is the normal WBC count?
4-11x10^9/litre
What is the ratio of RBC:Platelets:WBC
700:40:1
What are neutrophils in terms of proportion, structure and function?
50-70%
9-15um diameter
2-5 lobed nucleus
Granular cytoplasm
First line of defence against bacterial infection
What are eosinophils in terms of proportion, structure and function?
2-4%
10-12 um in diameter
Bilobular nucleus
Release toxic compounds
Allergies/asthma
Combat parasitic infections
What are basophils in terms of proportion, structure and function?
> 1% of WBC
8-10 diameter
Bilobed S shape nucleus
Large cytoplasmic granules with histamine and heparin
Inflammatory response
What are monocytes in terms of proportion, structure and function?
2-10%
20um diameter
Horseshoe shaped nucleus
Extensive cytoplasm
Tissue macrophages
Phagocytic
What are lymphocytes in terms of proportion, structure and function?
20-30% of WBC
6-15um
Role in all immunological defence mechanisms
What are the three types of lymphocytes?
T cells
B cells
NK cells
