Lecture 10 - Calcium II Flashcards
1
Q
Osetomalacia?
A
failure of bone to mineralise, low calcium and phosphate and osteoblast dysfunction, leads to rickets in children
2
Q
Causes of low vitamin d?
A
low exposure, enzyme induction of inactive metabolites in liver, and impaired 1alpha hyroxylase in kidney
3
Q
Pseudohypoparathyroidism?
A
high PTD but also high receptor resistance, short 4th and 5th metacarpal, mutation of Gs
4
Q
Autosomal dominant hypercalciuric hypocalcaemia?
A
CaSR activation, parathyroid reading serum Ca as higher than truth, PTH secretion becomes inappropriately low
5
Q
Familial Hypocalciuric Hypocalcemia?
A
normal PTH, family history of hypocalcemia, rato of fasting urine calcium to creatinine clearance
