lecture 10 and 11 sensory physiology Flashcards
sensory information
conscious or sub-conscious awareness of the internal or external environment
general somatic sensation
pain, temperature (thermal), tactile (eg. touch,pressure), proprioception (sense of limb in space)
special senses
smell, taste, vision, hearing, balance
sensory input- sensation-perception
sensory receptors are located
-at the end of a primary afferent neuron
or
-seperate receptor cell that signals to the primary afferent neuron
stimulus
energy or chemical that activates a sensory receptor
adequate stimulus
type of stimulus that is unique to sensory receptor
mechanoreceptors
respond to mechanical stimuli (pressure, stretch)
thermoreceptors
respond to temperature stimuli (cold,hot)
photoreceptors
respond to light wavelengths
chemoreceptors
respond to binding of chemicals
nociceptors
respond to pain (heat, mehanical, chemical)
sensory transduction
stimulus translate into an electrical response
- involves opening or closing of ion channels directly or through a second messenger
- becomes a graded potential called receptor potential
receptor potential
- magnitude of a receptor potential will decrease with distance from its origin
- if the afferent neuron is depolarized to threshold, AP will continue to fire and propagate to CNS
- increase in graded potential magnitude = increase in AP frequency
- increase in graded potential magnitude= increase neurotransmitter release at the afferent neuron’s central axon terminal
- does not determine amplitude of the AP
adaptation
- leads to a decrease in receptor sensitivity
- decrease in AP frequency in afferent neuron
- 2 types : slow adapting and rapidly adapting receptors
slow adapting (tonic) receptors
maintain a persistent or slow decaying receptor potential during constant stimulus
- little adaptation in response to a prolonged stimulus
- better at gaging the intensity of a stimulus than fast adapting
rapidly adapting (phasic) receptors
- quickly cease responding
- gage the change of a stimulus intensity better than slow adapting receptors
primary sensory coding
- conversion of a stimulus energy into a signal that conveys the relevant sensory information to the CNS
- important characteristics of stimulus : type, intensity and location
stimulus types (modalities)
modality: temperature, taste
submodalities : cold and hot/ sweet or salty
factors that effect stimulus intensity
- frequency of AP in a single afferent neuron
- summation : receptors on other branches of the same afferent neuron are activated
- recruitment : receptors on other branches of nearby afferent neurons are activated
summation coding (summation)
more receptors activated in the same afferent neuron as there is more pressure on the skin→ more AP’s
population coding (recruitment)
neurons next to each other are recruited as stimulus increases and is sensed by primary sensory neurons
stimulus location
AP will travel to CNS via a distinct pathway that is associated with that particular modality and body location
acuity
how precise we can locate and discern one stimulus from an adjacent one
→ greater convergence, less acuity
→greater size of receptor, less the acuity
→density of the sensory unit
→amount of overlap in nearby receptive fields
receptive field overlap
best respond to stimuli applied to center of receptive field due to high receptor density
-if stimulus acts on the periphery of the receptive field → cant differentiate intesity or location precisely
lateral inhibition
enables localization in a stimulus
-enhances the contrast between the center and periphery of a stimulated region
central control of afferent information
- reticular formation and cerebral cortex have descending inhibitory pathways
- via indirect synpase on axon terminal of primary afferent neuron
- via indirect synapse through interneurons
afferent sensory pathways carry what kind of info
conscious and not conscious information
- ascending pathways convey information about a single type of sensory information (eg. mechanreceptors →touch/pressure)
- pass through brainstem→thalamus→specific area on the cerebral cortex
second order neurons
the interneuron that the afferent neuron synapses onto
cortical association areas
-cortical association areas are outside the primary cortical sensory and motor areas
-regions closer will process information in a simple way
-regions further away will process information in more complicated ways
factors that affect perception
- sensory receptor mechanism
- emotions, personality and experience
- not all information entering the CNS gives rise to conscious sensation
- we lack suitable receptors for many types of potential stimuli
- drugs (hallucinations)
- mental illness
two people can be exposed to the same stimulus and have different perception from it
phantom limb
-damaged neuronal networks
-
somatosensory cortex includes
pre central gyrus
post central gyrus
motor cortex
coordinates our bodily movements
- primary motor area
- primary sensory area
- secondary motor and sensory areas (middle)
- anterior speech area (broca’s area)
- primary auditory area (more inside) secondary auditory area
- posterior speech area (wernickes area)
- primary visual area (more posterior) secondary visual area