[LEC] UNIT 3.2 Endocrinology Flashcards
Master Gland
Pituitary gland
Other name for APG
Adenohypophysis
T or F: The intermediate lobe of PG serves no function
T
Often obstructs images during MRI or CT
scans
Intermediate lobe
Acts as a storage and releases the two
hormones produced by the hypothalamus
Posterior Pituitary Gland
APG cells are large, polyhedral, and are supported by the delicate ______
reticular fibers
3 cell types found in APG
Chromophobe
Acidophilic
Basophilic
T or F: ONLY Acidophilic and Chromophobe are the two cells that are capable of secretion (secretory cells).
F
What produces Proopiomelanocortin and Endorphins?
ACTH
Precursor of MSH
Proopiomelanocortin
Meaning of MSH
Melanocyte Stimulating Hormone
GH is structurally related to
Prolactin
Human Placental Lactogen
Tropic or Trophic: GH
Trophic
Target of GH
Long bones
Other name for GH
Somatotropin
Inhibitor of GH
Somatostatin
Other name for Somatomedin C
IGF-1
Stimulants of GH
Sleep
Exercise
Fasting
Inhibitors pf GH
Somatomedin C
Hyperglycemia
T or F: Serum GH is undetected most of the day for unhealthy individuals
F
Meaning of IGF-1
Insulin-like Growth Factor-1
Feedback hormone of GH
Somatomedin C
T or F: GH antagonizes Insulin
T
GH causes an increase in glucose through
gluconeogenesis
lipolysis
a-antagonist
norepinephrine
B-antagonist
epinephrine
T or F: a-antagonist is a GH stimulant
T
Women tend to have higher growth hormone than
men because of
estrogen sensitization
Thyroid gland which is essential for GH function
T4
Condition wherein the thyroid gland is not functioning properly
Thyroxine deficiency
T or F: Thyroid function must be normal for GH therapy to be effective
T
Hormones that influence secretion and metabolic effects of GH:
CESTS
Thyroxine
Cortisol
Estrogen
Somatostatin
Somatotropin releasing factor
FSH stimulates growth of ________ in females
ovarian follicles
FSH stimulates _________ in males
sperm production
When FSH is produced, it will trigger the
selection of one egg, producing an ovarian
follicle, then turning it into
corpus luteum
Sertoli cells secrete
Androgen Binding Protein
ABP binds to which structure
seminiferous tubules
Stimulates testosterone production in males
LH
LH stimulates ________ in females
progesterone secretion
Cortisol is released in response to
Stress
Low blood glucose levels
3 layers of adrenal cortex
Zona Glomerulosa
Zona Fasciculata
Zona Reticularis
layer where aldosterone is produced
zona glomerulosa
Zone where cortisol is produced
zona fasciculata
zone where sex hormones are produced
zona reticularis
Hormones that require the use of plastic tubes since they adhere to glass
ACTH
regulates the thyroid gland’s production of
hormones, crucial for metabolism and various
physiologic functions
Thyroid stimulating hormones
promotes the uptake of iodide
TSH
process that transforms iodide to iodine
oxidation
swelling that occurs due to a lack of iodine in the diet
hypothyroidism
goiter
It needs priming by estrogen, thyroid hormones, and insulin to become functional
prolactin
T or F: Prolactin is also seen in men, but it does not act on mammary glands because males do not have receptors to produce milk
T
Prolactin suppresses testosterone production,
leading to
decreased libido
erectile dysfunction
The major circulating form of prolactin is the
non-glycosylated monomer
excessive production of milk
Galactorrhea
absence of menstruation, which means
that there are no egg cells produced
Amenorrhea
feedback hormone of GH
IGF-1
inhibitor of GH
somatostatin
target gland of GH
multiple tissues
feedback hormone of FSH
inhibin
Feedback hormone of LH
Estrogen
Testosterone
Estradiol
FSH and LH target
gonads
ACTH targets these zones of adrenal cortex
zona fasciculata
zona reticularis
feedback hormone of ACTH
cortisol
feedback hormone of TSH
T3 and T4
target tissue of prolactin
breast
feedback hormone of prolactin
unknown or itself
hormones released by PPG
where are they secreted?
oxytocin
vasopressin
supraoptic nuclei
paraventricular nuclei
PPG hormones are released by supraoptic nuclei and paraventricular nuclei of which structure
hypothalamus
contraction of uterus
Ferguson Reflex
Stimulates receptors on the pelvic floor and
the uterus
Ferguson reflex
Oxytocin is for ejection of milk primed with
estrogen
Oxytocin helps with milk _______ while prolactin
stimulates milk ________.
letdown
production
Plays a role in hemostasis at the _______ site
following delivery/birthing
placental
synthetic version of oxytocin; injected into the mother to induce labor when the pregnancy reaches 40 weeks or more
Pitocin
Maintains osmotic homeostasis by regulating water balance
Arginine Vasopressin or AVP or ADH
A potent pressor agent
Arginine Vasopressin
Principal regulator of ADH secretion:
increased pOsm
increase in _______ ________ occurs when sodium levels rise
plasma osmolality
Potent stimuli to ADH release:
emetic (dehydration)
Inhibitors of ADH release
ethanol
cortisol
AVP deficiency
Neurogenic DI (diabetes insipidus)
/Cranial DI