LEC 7 Flashcards

1
Q

what are opportunistic pathogens

A

infect immunocomporomised

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2
Q

what are primary pathogens

A

infect everyone

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3
Q

what eukaryotic cells have cell wall

A
  1. plant cells

2. fungal cells

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4
Q

what makes up cell wall of fungal cells

A
  1. chitin

2. ergosterol

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5
Q

what is basic mech of anti-fungal drugs

A

inhibit ergosterol synthesis

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6
Q

what are 3 types of fungi

A
  1. moulds
  2. yeasts
  3. dimorphic
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7
Q

what are 2 forms of thermally dimorphic

A
  1. mold

2. yeast

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8
Q

MOLDS what is thallus

A

body of fungus

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9
Q

MOLDS what are hyphae

A

filaments

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10
Q

MOLDS what are 2 types of hyphae

A
  1. coenocytic

2. septate

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11
Q

MOLDS what are coenocytic hyphae

A

no separation bw cells in filaments

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12
Q

MOLDS what are septate hyphae

A

separation bw cells in filaments

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13
Q

YEAST what is shape of yeast

A

oval

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14
Q

YEAST how do yeast reproduce

A

budding

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15
Q

YEAST how do pseudo hyphae form

A

bud fails to detach

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16
Q

YEAST what do candida albicans use as means of invading tissue

A

pseudo hyphae

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17
Q

YEAST what is characteristic of sacchromyces

A
  1. yeast

2. non pathogenic

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18
Q

YEAST what are growth conditions of yeast

what are growth conditions of molds

A
  • yeast ==> anaerobic + aerobic

- molds => aerobic

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19
Q

DIMORPHIC when will dimorphic fungi grow as molds

A

low temps

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20
Q

DIMORPHIC when will dimorphic fungi grow as yeasts

A

body temps

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21
Q

DIMORPHIC how do dimorphic fungi cause infection

A

conidia in air

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22
Q

DIMORPHIC what form releases conidia in air

A

molds

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23
Q

DIMORPHIC what kind of fungi causes sporothrix

A

dimorphic

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24
Q

DIMORPHIC how does dimorphic fungi cause sporothrix

A

introduced into wound after trauma

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25
DIMORPHIC what is lymphangitis
inflammation of walls of lymphatic vessels
26
what are conidia important for
1. repro | 2. identification (under microscope)
27
what is a fungal disease
mycosis
28
what are fungal diseases
mycoses
29
what are 3 types of mycoses
1. superficial 2. cutaneous 3. systemic
30
SUPERFICIAL where are fungi in superficial
1. outer layer of skin | 2. hair shaft
31
CUTANEOUS where are fungi in cutaneous
deeper layer of skin
32
CUTANEOUS what are 2 types of cutaneous mycoses
1. athlete's foot | 2. ring worm
33
CUTANEOUS what kind of fungi cause cutaneous mycoses
dermatophytes
34
CUTANEOUS what are dermatophytes
use keratin as food source
35
CUTANEOUS what is name of clinical diseases caused by dermatophytes
tinea
36
SYSTEMIC where are systemic fungi
organs
37
SYSTEMIC what kind of pathogens casue systemic mycoses
1. opportunistic | 2. primary
38
what is antiseptic
disinfectant used on skin
39
what is disinfectant
chemical used to kill many microorganisms
40
what is aseptic
technique used to exclude micro organisms
41
what is pasteurization
heat treatment
42
what is sanitization
reducing num of micro organisms to lvl that meets public health standards
43
what is sterilization
chemical that kills all microorganisms
44
what is glutaraldehyde
1. bactericidal chemical | 2. sterilizing chemical
45
what direction does air flow
pos pressure to neg pressure
46
what is pos pressure room
air flows from inside to outside
47
what kind of patient is put into pos pressure room
susceptible to infectious disease
48
what is neg pressure room
air flows outside to inside
49
what kind of patient is put into neg pressure room
causes infectious disease
50
what are 2 means of sterilizing using heat
1. hot air | 2. autoclaving (moist heat)
51
what means of sterilizing using heat needs to be tested
autoclaving
52
how is autoclaving tested
spore test
53
what does effective sterilization depend on
presence of organic material
54
what are steps of spore test
1. autoclave ampule containing nutrient media + endospores 2. incubate sample 3. look for growth
55
what is indication of growth
colour change
56
why is colour change indication of growth
1. spores germinated 2. bacteria grew 3. bacteria metabolized 3. bacteria produced basic / acidic compounds
57
what 4 chemicals can sterilize
1. halogens 2. aldehydes 3. ethylene oxide 3. per-oxygen
58
when can halogens sterilize
1. exposure to proper concentration | 2. exposure for sufficient amount of time
59
what can alcohols not kill
1. endospores | 2. naked viruses
60
what can halogens act as
1. disinfectant | 2. sterilizing chemical