LEC 2 Flashcards
what are meninges
membranes that cover brain and spinal cord
how many meninges
3 (dura, arachnoid, pia)
where is CSF located
arachnoid
what should CSF not have
microorganisms
what is gram morphology of N.m
gram neg diplococcus
what does N.m have around outer cell wall
capsule made of polysaccharides
what is mode of transmission
droplet
what is droplet transmission
large mucous molecules expelled through cough + sneeze
VIRULENCE FACTORS where is endotoxin / lipid A located
cell wall
VIRULENCE FACTORS what does endotoxin of N.m cause (4)
- blood clotting
- DIC
- hemorrhage
- shock
VIRULENCE FACTORS what does hemorrhage lead to
- petechiae
2. purpura
VIRULENCE FACTORS what are petechiae
small purple spots
VIRULENCE FACTORS what are purpura
large purple spot
VIRULENCE FACTORS what does capsule of N.m cause
inactivation of WBC trying to phagocytize it
VIRULENCE FACTORS what does inactivation of WBC by N.m cause
N.m replication in CSF