LEC 6 Flashcards
PLASMA MEMBRANE + MOVEMENT
Plasma membrane
cell membrane
phospholipid bilayer
Plasma membrane components (3)
- phospholipids
- cholesterol
- proteins
Purpose of cholesterol in cell membrane
increases strength and rigidity
Purpose of proteins in cell membrane
embedded in membrane
helps move materials in and out of the cell
communication b/w cells
Receptor proteins def (2)
embedded in the plasma membrane
transmit information (to make something happen in the cell)
How do receptor proteins work?
signaling molecule binds to receptor site and triggers a series of chem reactions
Open Channel (2)
always open
allowing free movement in/out of the cell
Gated channel (3)
Is closed
limits what can enter/leave the cell
“Right” material triggers or signals it to open
Transport Protein (2)
Allows specific molecules to enter/leave the cell
Protein physically changes shape to transport the material
Glycoprotein
Has specific carbohydrate groups attached to the surface
Used in cell-to-cell recognition and communication
Membrane polar or non-polar?
polar
Types of movement across the membrane ()
- Diffusion
- Active transport
- Bulk transport
- Osmosis
Diffusion
Movement of molecules from one region to another
Passive Diffusion
Move from area of high concentration to that of low concentration until equilibrium
Passive Diffusion (through lipid bilayer)
(2 + example)
- allows some molecules through and restricts others
- Small, uncharged non-polar molecules pass easily (dissolve)
e.g. O2, CO2, urea
Passive Diffusion (through channels)
- water and many ions diffuse though
- some channels are always open, others gated
- gated channels for Na, K, Ca
Facilitated Diffusion steps (3)
- molecule attaches to “transport” or “carrier” protein
- protein changes shape to physically transfer the molecule to the other side of the membrane and release it
- “carrier” protein returns to OG shape
Facilitated Diffusion example
Glucose and other simple sugars
Osmosis
diffusion of water across a selectively permeable membrane
Osmosis direction of water
opposite direction of the solutes
Active Transport
needs energy and moves against the concentration gradient (from low to high concentration)
Endocytosis
into the cell
sodium-potassium pump
Exocytosis
out of the cell
What is endocytosis & exocytosis used for? (2)
- Larger molecules that won’t “fit” through channels or proteins
- Bulk transport of several kinds of molecules at the same time
Endocytosis steps
Exocytosis steps
Tonicity
the concentration of solutes in two fluids (inside and outside of the cell)
Water will always move to the area with the _____________ solute concentration
higher
Types of extracellular solutions (3)
- Isotonic
- Hypertonic
- Hypotonic
Isotonic
solute concentrations equal both inside and out
Water movement is equal
Hypertonic
higher solutes outside compared to inside
Water moves OUT and cell undergoes crenation
Hypotonic
higher solutes inside compared to outside
Water moves INTO the cell and the cell undergoes lysis
Crenation
cells are exposed to a hypertonic solution
Lysis
cells are exposed to a hypotonic solution will swell and burst