[Lec 4] iClicker Question: Genome Structure, Chromatin, and the Nucleosome

Question 1

Based on what you know about transposable elements, which of the following statements would you expect to be true;

A) There are more transposons than retrotransposons

B) There are more retrotransposons than transposons

C) There are an equal number of transposons and retrotransposons

Answer 1

b.

Question 2

Why would supercoiled DNA migrate faster than relaxed circular DNA?

A. Supercoiling makes it more compact, so it migrates faster
B. Supercoiling changes the charge to mass ratio, so it migrates faster
C. Supercoiling gives it higher energy, so it migrates faster

Answer 2

a.

Question 3

What would happen if the chromatin was treated with excess MNase?

A. The DNA would be degraded to single nucleotides.
B. The DNA would be degraded to 150 bp fragments.
C. It would be a smear, like naked DNA.
D. There would be no difference.

Answer 3

b.

Question 4

Which modifications will “open up” the histone tail allowing the DNA to be more easily transcribed?

A) Phosphorylation

B) Acetylation

C) Methylation

D) Both A and B

E) Both A and C

Answer 4

d.