[Lec 1] iClicker Questions: Structure of DNA Flashcards
When Mendel was studying the pea plants, he was trying to determine both the genotype and phenotype. These terms are best described as:
A) Genotype is the physical structure and phenotype is the genetic composition
B) These phrases can be used interchangeably
C) Phenotype is the physical structure and genotype is the genetic composition
D) Phenotype refers to the peas themselves and genotype refers to the pea flowers
c.
What conclusions can be drawn from this experiment?
A. Polysaccharide coat from dead S strain enveloped R strain, making it lethal
B. R strain gained the ability to make a polysaccharide coat when mixed with the dead S strain.
C. Toxin in S strain is activated by injection with R strain
b.
True or False: Griffith’s experiments definitively prove that DNA is the heritable genetic material. A) True
B) False
b.
Given what you already know about genes and what you have read, which treatment will destroy the ability of the bacteria to be transformed?
A) RNase
B) DNase
C) Protease
D) All three of the above
E) None of the above
b.
The Hershey and Chase experiments using 35S- and 32P- labeled T2 bacteriophage supported the hypothesis that DNA is the genetic material because __________.
A) 35S-labeled phage protein entered the host cell
B) New T2 progeny contained 35S-labeled protein
C) 32P-labeled phage DNA did not enter the host cell
D) New T2 progeny contained 32P-labeled DNA
d.
From Chargaff’s rule, you can conclude for double stranded DNA that A+C=G+T
A) True
B) False
a.
Ambitious NASA researchers have discovered life on Mars. They have found that its DNA is double stranded but with 4 different bases: M, H, E, K. Assuming that it follows the known rules of DNA on Earth, that M and H are purines and that H pairs with K, which of the following is true:
A) M+E=H+K
B) M+H=E+K
C) M+K=E+H
D) Both A and B
E) Both B and C
e.
Given the DNA sequence 5ʹ′-AGCCTA-3ʹ′, which of the following represents the complementary strand of DNA? A) 5ʹ′-ATCCGA-3ʹ′ B) 5ʹ′-TCGGAT-3ʹ′ C) 5ʹ′-AGCCTA-3ʹ′ D) 5ʹ′-TAGGCT-3ʹ′
d.
You are a DNA-binding protein sampling the genome along the minor groove. You come across the chemical signature AHA. What base pair is this?
A. G-C
B. G-C or C-G
C. A-T
D. T-A
E. A-T or T-A
e.
You want to get to the bottom of things, so you recruit a DNA-binding protein that prefers to sample the major groove. This time you read out MADA.
A. Okay, it’s A-T
B. No it’s totally T-A
C. Still can’t tell!
b.
