LEC - 4 - Dosage Levels... Flashcards

1
Q

The amount of drug taken at one time, which can be expressed as the weight of the drug (e.g., 250 mg), volume of drug solution (e.g., 10 ml, 2 drops), the number of dosage forms (e.g., 1 capsule, 1 suppository), or some other quantity (e.g., 2 puffs).

A

Dosage

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2
Q

Dosage can be expressed as:

A

weight of the drug (e.g., 250 mg)
volume of drug solution (e.g., 10 ml, 2 drops)
number of dosage forms (e.g., 1 capsule, 1 suppository)
some other quantity (e.g., 2 puffs)

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3
Q

(e.g., 250 mg)

A

weight of the drug (e.g., 250 mg)

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4
Q

(e.g., 10 ml, 2 drops)

A

volume of drug solution

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5
Q

(e.g., 1 capsule, 1 suppository)

A

number of dosage forms

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6
Q

(e.g., 2 puffs)

A

some other quantity

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7
Q

The frequency at which drug dosages are given. Examples include 2.5 ml twice a day, one tablet three times a day, or one injection every four weeks.

A

Dosage Regimen

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8
Q

Is the amount of a drug that produces the desired response.

A

Effective Dose

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9
Q

Dosage Levels:

A

Minimum Dose
Maximum Dose
Loading Dose
Maintenance Dose
Toxic Dose
Lethal Dose

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10
Q

The smallest dose of a medicine or drug that will produce a therapeutic effect.

A

Minimum Dose

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11
Q

The largest dose of a medicine or drug that is consistent with safety.

A

Maximum Dose

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12
Q

A higher dose than that usually used for treatment, given when the drug effects are needed quickly.

A

Loading Dose

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13
Q

The amount of medication administered to maintain a desired level of the medication in the blood.

A

Maintenance Dose

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14
Q

The amount of a drug that causes untoward symptoms in the majority of persons.

A

Toxic Dose

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15
Q

The quantity of an agent that will or may be sufficient to cause death.

A

Lethal Dose

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16
Q

Common Responses to medication include:

A

Desired Effect
Side Effect
Adverse Effect
Allergic Response
Anaphylactic Response
Idiosyncratic Response
Paradoxical Reaction

17
Q

When the drug does what it is supposed to do, achieving the therapeutic goal.

A

Desired Effect

18
Q

Example: Taking aspirin to reduce temperature.

A

Desired Effect

19
Q

Mild but annoying responses to medication.

A

Side Effect

20
Q

Example: Stomach pain caused by paracetamol/acetaminophen.

A

Side Effect

21
Q

More severe symptoms or problems that arise due to the medication.

A

Adverse Effect

22
Q

Example: Severe gastric bleeding from an ulcer caused by aspirin.

A

Adverse Effect

23
Q

An antigen-antibody reaction where the body develops hives, rashes, itching, or swelling of the skin.

A

Allergic Response

24
Q

Example: A rash or shortness of breath occasionally seen in patients allergic to aspirin.

A

Allergic Response

25
Q

A severe form of allergic reaction that is life-threatening.

A

Anaphylactic Response

26
Q

Example: Severe shortness of breath, possibly leading to breathing cessation or cardiac collapse.

A

Anaphylactic Response

27
Q

Strange, unique, or unpredicted reactions.

A

Idiosyncratic Response

28
Q

Example: Blood in the urine caused by aspirin.

A

Idiosyncratic Response

29
Q

Reactions that are the opposite of what would be expected.

A

Paradoxical Reaction

30
Q

Example: An analgesic (pain reliever) causes an increase in pain, or sedatives prescribed for adults cause hyperactivity in children.

A

Paradoxical Reaction