Lec 22 - Zoonotic TB, pasteurellosis, coccidioidomycosis Flashcards
what is the scientific name for zoonotic tuberculosis (zTB)
mycobacterium bovis and mycobacterium caprae
what are the species involved with zTB
bovines, caprines, ovines, porcines (domestic and wild), camelids, mustelids (wild), and cervids
what are the geographic location of zTB
in order from most to least burdened continents/areas: africa, southeast asia, western pacific, eastern Mediterranean
what are the clinical signs of zTB in animals
loss of body condition, intermittent pyrexia, enlarged superficial lymphnodes, cough, dyspnea, diarrhea and constipation
what are the clinical signs of zTB in humans for the respiratory form
bloody sputum, pleuritic chest pain, and asthenia
what are the clinical signs of zTB in people with the extrapulmonary form
ocular disorders, infertility and abortion
describe the antemortem lesions in zTB
nodular skin lesions called tuberculous chancres, described as “firm red papules that become painless shallow ulcers on the skin”
what is the morbidity/mortality of zTB
morbidity is 147,000 cases per year
mortality is 12,500 deaths per year
what is the animal to animal transmission of zTB
animal to animal transmission occurs through inhalation of droplets produced by infected animals in close quarters, ingestion of bacteria through milk, or ingestion of bacteria through feed/water
what is the animal - human transmission of zTB
transmission occurs though inhalation of droplets produced by infected animals, direct contact with cutaneous penetration and ingestion of bacteria through unpasteurized milk products
what is the treatment for humans with zTB
humans get a round of antibiotics for 6-12 months
how are animals with TB treated
culling
what is a concern of countries trying to get rid of zTB
antimicrobial resistance to treatment is a concern. mycobacterium bovis is naturally resistant to the main antibiotic pyrazinamide used the treat TB
what is the common and scientific name for pasteurellosis in cattle
shipping fever
mannheimia haemolyticia and P.multocida
what is the common name for pasteurellosis in birds
Fowl cholera
What is the common name for pasteurellosis in rabbits
snuffles
what is the common name for pasteurellosis in swine
atrophic rhinitis
what is the most clinically relevant spp of pasteurella in domestic and wild animals
pasteurella multocida