Lec 2 - Cholesterol Flashcards

1
Q

body can synthesize all the blank it needs like in the case of vegans

A

cholesterol

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2
Q

three important thigns that cholesterol does

A

membrane, precursor for bile acids and steroid hormones

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3
Q

excess cholesterol can precipitate to form blank, and can lead to blank which increases heart attacks and strokes

A

gallstones, arterial plaques

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4
Q

cholesterol causes a membrane to become blank

A

stiffer

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5
Q

cholesterol is the animal equivalent to the blank of a plant

A

cell wall

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6
Q

as tissues cool, cholesterol keeps our membranes fluid by blank fluidity

A

increasing

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7
Q

most cholesterol is made in the blank and blank

A

liver, intestinal mucosa

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8
Q

cholesterol has blank carbons and is derived from acetyl coA via blank

A

27, isoprenes

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9
Q

rate limiting enzyme of synthesis of cholesterol

A

hmg coA reductase

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10
Q

bio synthesis of cholesterol slide is important

A

ok

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11
Q

this promotes expression of the hmg coA reductase gene and is a transcription factor involved in regulating cholesterol biosynthesis

A

SREBP

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12
Q

waxy lipid compound obtained from diet or by biosynthesis from acetyl coA

A

cholesterol

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13
Q

other isoprenoids important in biochem that we cant make

A

vitamin a,e,k

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