Lec 2 - Cholesterol Flashcards
body can synthesize all the blank it needs like in the case of vegans
cholesterol
three important thigns that cholesterol does
membrane, precursor for bile acids and steroid hormones
excess cholesterol can precipitate to form blank, and can lead to blank which increases heart attacks and strokes
gallstones, arterial plaques
cholesterol causes a membrane to become blank
stiffer
cholesterol is the animal equivalent to the blank of a plant
cell wall
as tissues cool, cholesterol keeps our membranes fluid by blank fluidity
increasing
most cholesterol is made in the blank and blank
liver, intestinal mucosa
cholesterol has blank carbons and is derived from acetyl coA via blank
27, isoprenes
rate limiting enzyme of synthesis of cholesterol
hmg coA reductase
bio synthesis of cholesterol slide is important
ok
this promotes expression of the hmg coA reductase gene and is a transcription factor involved in regulating cholesterol biosynthesis
SREBP
waxy lipid compound obtained from diet or by biosynthesis from acetyl coA
cholesterol
other isoprenoids important in biochem that we cant make
vitamin a,e,k