Learning and Memory Flashcards

(65 cards)

1
Q

Learning

A

Lasting change in behaviour resulting from experience

Acquiring new information and skills

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2
Q

Learning - Forms, Classical Conditioning, Pavlov

A

Pairing of two stimuli causes a change in response to one

Dogs study

Unconditioned stimulus produces an unconditioned response
Pairing UCS with a neutral stimulus produces UCR
After multiple pairings, NS will produce the CR without need for the UCS

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3
Q

Learning - Forms, Operant Conditioning, Skinner

A

Responses followed by reinforcement or punishmenet will be strengthened or weakened respectively

Rat study

Trained rats to press a level for food or avoid an area using shocks

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4
Q

Learning - Forms, Delayed Responses

A

Happenings which affect much later behaviour

e.g. eating a poisonous berry, being ill and then being averse to the berries forever

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5
Q

Learning - Forms, Insightful Behaviours

A

Searching or problem-solving to gain reward

e.g. monkey using a tool to get food from a box

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6
Q

Learning - Forms, Imitation

A

Copying of others behaviour

e.g. birdsong (not paired with reward)

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7
Q

Learning - Mechanisms, Pavlov

A

Conditioning strengthens to connections between the newly conditioned stimulus and usual unconditioned response via the original unconditioned stimulus

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8
Q

Learning - Mechanisms, Lashley 1930

A

If learning is a result of neural connections, a knife cut should abolish the learning
If specific connections explain learning of specific information, the size of physical damage should be proportional to the amount of retardation caused

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9
Q

Learning - Mechanisms, Lashley 1930, Mass Action

A

Assumption that the cortex works as a whole

If more of the cortex is active, learning will be more effective

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10
Q

Learning - Mechanisms, Lashley 1930, Engram

A

The physical representation of learning within the brain
e.g. the synapse connection

Located in the cortex

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11
Q

Learning - Mechanisms, Lashley 1930, Equipotentiality

A

All of the cortex contributes to learning equally, so much so that if one area were the be damaged, other areas can compensate for its function

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12
Q

Learning - Mechanisms, Thompson 1986, Engram

A

The engram of learning is located in the cerebellum

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13
Q

Learning - Mechanisms, Thompson 1986, Lateral Interpositus Nucleus

A

Inhibition of the LIN inhibits learning
When learning is suppressed, LIN shows no activity

Activity in LIN is required for retention and extinction of information

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14
Q

Learning - Mechanisms, Thompson 1986, Red Nucleus

A

Important for showing a learned response

Unsure whether you still learn implicitly as it cannot be shown

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15
Q

Memory

A

Process of acquiring knowledge and skills manifested in behavioural changes, based on an ability to retain what is learned

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16
Q

Memory - Encoding

A

Receiving, processing and combining information

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17
Q

Memory - Storage

A

Permanently recording encoded information

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18
Q

Memory - Retrieval, Recall, Recollection

A

Being able to call back the information from storage

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19
Q

Memory - Short-Term Memory, Hebb 1949

A

Holds information that has just been given for around 20-30 seconds

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20
Q

Memory - Short-Term Memory, Atkinson & Shiffrin 1968

A

All information must go via STM and be rehearsed before being consolidated to LTM

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21
Q

Memory - Working Memory, Baddeley & Hitch 1994

A

Temporary storage of information that is activley attended to and able to be worked on for a period of time

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22
Q

Memory - Working Memory, Chafee & Goldman-Rakic 1998

A

Delayed response task with single-unit neuron recording in parietal and prefrontal cortex

Shows that parietal activity can compensate for other areas of the brain during learning and memory consolidation

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23
Q

Memory - Working Memory, Hedden & Garbiela 2004

A

Lateral prefrontal cortex, primary visual cortex and hippocampus volume decrease with age

Can explain memory decline

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24
Q

Memory - Working Memory, Rosen et al 2002

A

Older individuals with intact memory show greater activity in lateral PFC, primary visual cortex and hippocampus

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25
Memory - Declarative
Knowledge of facts requiring conscious awareness Fast learning with little repetition Verbally expressed
26
Memory - Procedural
Implicit knowledge of skills and abilities Slow learning requiring much repetition Expressed in performance
27
Memory - Episodic
Personal experiences and events, including the emotions and sensations of the occurrence
28
Memory - Semantic
Facts of the world not related to specific events e.g. word meanings
29
Memory - Amnesia
Loss of memory
30
Memory - Amnesia, HM
Removal of hippocampus Difficulty forming LTM STM and WM intact Poor declarative memory Intact implicit memory
31
Memory - Amnesia, HM, Milner 1958
HM could remember a string of numbers by creating abstract strategies (procedural memory) to help remember them If put under cognitive load or distracted, recall was not possible due to inability to consolidation the string
32
Memory - Amnesia, Shrager et al 2008
Damage to medial temporal lobe left WM intact | If tasks were dependent on LTM, patients extremely impaired
33
Memory - Amnesia, Retrograde
Loss of memories prior to brain damage
34
Memory - Amnesia, Anterograde
Loss of ability to form new memories
35
Memory - Amnesia, KC
Bilateral hippocampal lesion Anterograde amnesia Episodic amnesia
36
Memory - Amnesia, KC, Rosenbaum et al 2005
KC able to use information about self from prior to incident but cannot form new memories or remember past experiences Supports dissociation between episodic and semantic memory
37
Memory - Amnesia, Tranel & Damasio 1993
Amnesia patients were exposed to a nurse (neutral / pleasant / unfriendly) Later shown photos and will prefer the pleasant nurse Cannot recall seeing the nurses Implicit memory intact, declarative not
38
Memory - Amnesia, Stickgold et al 2000
Amnesiacs played tetris and still had hypnagogic / dreaming experiences about the game despite not being able to recall playing Lack of explicit, declarative memory
39
Memory - Neural Basis, Amygdala
Involved in fear-conditioning
40
Memory - Neural Basis, Parietal Lobe
Active when associating details of memories Active during EWT Damage results in poor episodic memory during spontaneous elaboration
41
Memory - Neural Basis, Temporal Lobe
Hub for communication between regions of the brain | Linked to semantic dementia
42
Memory - Neural Basis, Hippocampus
Link between amnesia and hippocampus damage suggests its involvement in memory
43
Memory - Neural Basis, Hippocampus, Zola et al 2000
Dmaage impairs matching-to-sample tasks showing impaired episodic, declarative memory
44
Memory - Neural Basis, Hippocampus, HM
Could not rememeber completing tasks e.g. mirror drawing | Skill improved due to procedural memory
45
Memory - Neural Basis, Hippocampus, Spatial Memory, Goodrich-Hinsaker & Hopkins 2010
Radial maze for rats Rats failed to navigate the same maze multiple times if had hippocampus damage Simulated to find same results if using VR on humans
46
Memory - Neural Basis, Hippocampus, Spatial Memory, Maguire et al 2000
Taxi drivers, who rely heavily on spatial memory, show enhanced hippocampus activity and volume
47
Memory - Neural Basis, Hippocampus, Contextual Memory, Kamarowski et al 2009
Individual neurons respond to specific contexts
48
Memory - Neural Basis, Hippocampus, Protein
Inhibition of hippocampul protein impairs memory consolidation Enhanced release of cortisol during emotional events results in amygdala and hippocampal activity Emotional events are remembered better
49
Memory - Neural Basis, Basal Ganglia
Resembles a horn Composed of globus pallidua, putamen and caudate nucleus Associated with planning of motor movement and coordination, important in procedural learning Damage results in Parkinson's and inability to learn implicitly
50
Memory - Neural Basis, Basal Ganglia, Moody et al 2010
Demonstrated the role of basal ganglis in implicit habit learning Parkinson's patients, who have inability to learn implicity, only learned a technique if they showed awareness of participating If they were not aware they could not learn due to inability to have learned implicitly also
51
Memory - Neural Basis, Prefrontal Cortex
Linked to reward choice comparisons and memory suppression | Impact on classical conditioning
52
Memory - Neural Basis, Prefrontal Cortex, Depue et al 2007
Memories are suppressed by different areas of prefrontal cortex Inferior PFC suppresses sensory memories Medial PFC suppresses emotional memories
53
Memory - Biochemical Mechanism
Patterns of neural acitivty leave paths in the brain for physical change
54
Memory - Biochemical Mechanism, Hebbian Synapse
Simultaneous presynaptic and postsynaptic activity strengthens the effectiveness of a neuron
55
Memory - Biochemical Mechanism, Hebbian Synapse, Long-Term Depression
Prolonged decreased sensitivity | Possibly due to extended understimulation
56
Memory - Biochemical Mechanism, Hebbian Synapse, Long-Term Potentiation
When axons are bombarded with stimulation they become more responsive and synapses remain potentiated (with neurotransmitters) for a longer time Dependent on glutamate
57
Memory - Biochemical Mechanism, Hebbian Synapse, Long-Term Potentiation, Assumptions
Specificity where only active neurons are strengthened to improve efficiency Associativity where weak inputs are paired with stronger ones to enhance neuronal responses by summation Cooperativity where simulataneous stimulation increases LTP by summation
58
Memory - Biochemical Mechanism, Glutamate Synapse
Glutamate is an excitatory neurotransmitter
59
Memory - Biochemical Mechanism, Glutamate Synapse, AMPA
Glutamate receptors which open Na+ channels to allow cell depolarisation
60
Memory - Biochemical Mechanism, Glutamate Synapse, NMDA
Glutamate receptors which open Na+ channels to allow cell depolarisation Also open Ca++ channels if membranes are already polarised, triggerring neurotransmitter release
61
Memory - Biochemical Mechanism, Glutamate Synapse, Magnesium
Blocks NMDA receptors at resting potential so no neurotransmitter is released and postsynaptic membranes cannot be stimulated Is blocked from NMDA receptors at excitation threshold, allowing postsynaptic stimulation
62
Memory - Biochemical Mechanism, Glutamate Synapse, Ca++
Allowed into the cell after Mg+ is blocked from NMDA receptors Triggers CaMk11 proteins (e.g. CREB) in the nucleus to alter gene expression, which alters glutamate responsivity
63
Memory - Biochemical Mechanism, Glutamate Synapse, Gene Alteration
Caused by CaMk11 / CREB Increase glutamate release, dendrite number, AMPA sensitivity, increasing postsynaptic stimulation
64
Memory - Biochemical Mechanism, Glutamate Synapse, Postsynaptic Stimulation
Excessive stimulation causes release of retrograde neurotransmitters
65
Memory - Biochemical Mechanism, Glutamate Synapse, Retrograde Neurotransmitters
Modify presynaptic membranes Decrease excitation threshold so AP are sent by weaker stimulation Increase neurotransmitter release from more sites meaning more in the synapse for longer, resulting in LTP Expand axons to fit more Na+ channels to allow more AP to fire