Large Intestine - Non-IBD colitides

Question 1

Main subtypes of microscopic colitis?

Which is more common?

Treatment?

Answer 1

Lymphocytic colitis and collagenous colitis

Lymphocytic

Budesonide

Question 2

Acute severe watery diarrhea they can last for months to years likely due to an unidentified infectious agent. Named after this city?

Answer 2

Brainerd, MN

Question 3

Mechanism of diversion colitis?

Treatment?

Answer 3

Absence of material for bacteria to ferment into short chain fatty acids (these normally provide direct energy to colonic epithelial cells)

Surgical restoration of colonic continuity or short Chain fatty acid enemas

Question 4

Treatment options for chronic radiation proctitis?

Answer 4

APC,
Sucralfate retention enemas
Hyperbaric oxygen therapy

Question 5

Drug mechanisms that lead to checkpoint immune mediated colitis?

Answer 5

PD-1, PDL-1, and CTLA-4 inhibitors

Question 6

Treatment for checkpoint inhibitor induced colitis?

Second line? Third line?

Answer 6

Steroids

Infliximab

Vedolizumab

Question 7

Treatment for SCAD?

Answer 7

Cipro/Flagyl or 5ASA

Question 8

Vascular supply: SMA? IMA?

Answer 8

Cecum, ascending colon, 2/3 transverse colon

Distal transverse colon, descending and sigmoid colon, and rectum

Question 9

Rectum receives blood supply from?

Answer 9

IMA and internal iliac arteries (via middle and inferior rectal arteries)

Question 10

Artery that runs along the entire length of the colon and gives rise to the vasa recta?

Answer 10

Artery of Drummond

Question 11

X-ray pattern in acute Colonic ischemia?

Answer 11

Thumbprinting Pattern

Question 12

Single mucosal linear ulceration along the longitudinal axis of the colon is very suggestive of?

Answer 12

Single stripe sign - ischemic colitis

Question 13

Pathognomonic finding of ischemic colitis on histology?

Answer 13

Ghost cells (preserved cell outline without cellular content)