Large Intestine - Infection Flashcards
Infectious watery diarrhea seen in a patient on PPI?
Pathogenicity? Extent of epithelial invasion?
Vibrio cholarae
Enterotoxin
Noninvasive
Watery diarrhea And soft tissue infection, most commonly in Japan?
Treatment?
Vibrio parahaemolyticus
Supportive (no antibiotics)
Leading cause of seafood related deaths in the USA?
Patients with this disease are particularly susceptible? Why?
Non-G.I. manifestations?
Vibrio vulnificus
Cirrhosis (immune system dysfunction related to decrease complement levels)
Blistering skin lesions
Most common cause of travelers diarrhea?
Heat labile toxin stimulates? Heat stable toxin?
Enterotoxigenic E. coli
Adenylate Cyclase
Guanylyl cyclase
Causes an invasive diarrhea similar to shigellosis?
Enteroinvasive E. coli
Diarrheal illness in infants in developing countries?
Characteristic histologic feature?
Enteropathogenic E. coli
Attachment and effacement
Cause of bloody diarrhea that can resemble ischemic colitis?
Detect on this special medium?
Enterohemorrhagic E. coli
sorbitol-MacConkey
Causes acute and chronic watery diarrhea in children in developing countries and in HIV patients?
Enteroaggregative E. coli
This parasite existing two forms, cysts and trophozoites, and affects travelers to tropical areas with poor sanitation
Endoscopic findings?
How to diagnose invasive disease?
Entamoeba Histolytica
Amebic Colitis with flask-shaped ulcers
Red blood cells inside trophozoites
This parasite existing two forms, cysts and trophozoites, and Is the most common cause of human parasitic disease in the US?
If non-invasive tests are inconclusive can do this?
Giardia
Duodenal aspirate
Most common Pathogen that leads to food poisoning?
Food poisoning linked to ham, pork, and pastries?
Norovirus
Staph aureus
Hypervirulent C diff strain?
Which is the more potent c diff toxin?
NAP1/BI/027 aka epidemic strain
Toxin B
Histology this shows a “Summit” or “volcano“ lesion?
C diff (Pseudomembrane biopsy)
Monoclonal antibody against c diff toxin B?
Bezlotoxumab
