Biliary tract Flashcards

1
Q

Increased risk of malignancy in these choledochal cyst types?

Types of cancers?

A

1,4,5

cholangiocarcinoma > Squamous cell carcinoma, anaplastic, undifferentiated

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2
Q

Choledochal Cysts type 1A, 1B, 1C - What is dilated? Involvement of the intrahepatic ducts? Is area cystic duct enters dilated?

Management?

A

1A – entire extra hepatic biliary tree. Spares intrahepatic bile ducts. Cystic duct from dilated CBD.

1B - Focal dilation of extra
hepatic bile duct. Intrahepatic bile ducts not involved. Cystic duct from normal CBD.

1C - fusiform dilation of entire extra hepatic biliary tree. Extends into intrahepatic bile ducts. Cystic duct from dilated CBD

Management: complete excision and hepaticojejunostomy

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3
Q

Choledochal cysts - type II and III?

Management?

A

Type II - True diverticulum of the extra hepatic bile duct
Management: cyst excision

Type III - dilation of the distal, intraduodensl portion of the CBD
Management: sphincterotomy

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4
Q

Choledochal cysts - type IVa and type IVb?

Management?

A

type IVa - Multiple intra- and extrahepatic bile duct dilations

type IVb - Multiple dilations of the extra hepatic biliary tree

Management: cyst excision and hepaticojejunostomy; segmental hepatectomy of localized intrahepatic liver involvement

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5
Q

Choledochal cysts - type V?
Management?

A

Caroli disease – multiple dilations of the intrahepatic bile ducts

Segmental hepatectomy if localized; otherwise liver transplant

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6
Q

Most common type of gallstone?

Black stones associated with?

Brown stones associated with?

A

Cholesterol stones

Chronic hemolytic anemia

Biliary stasis and infection

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7
Q

Impacted cystic duct stone obstructing the common hepatic duct – named?

A

Mirizzi syndrome

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8
Q

Gastric outlet obstruction due to impaction of a gallstone in the pylorus or duodenum - named?

A

Bouveret’s Syndrome

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9
Q

Gallstone Obstructing terminal ileum - named?

A

Gallstone ileus

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10
Q

Who/what conditions qualify for prophylactic cholecystectomy?

A

-Porcelain gallbladder
-abnormal pancreaticobiliary junction
-gallbladder polyps over 1 cm

-native Americans

-morbidly obese patients undergoing bariatric surgery
-patients who undergo resection of small intestinal NETs with planned treatment with somatostatin analogs

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11
Q

Most common site of a bile leak after cholecystectomy?

A

Cystic duct stump ; ducts of Luschka

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12
Q

Gallbladder polyps caused by hyperplasia of the gallbladder mucosa associated with foamy macrophages?

A

Cholesterolosis

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13
Q

Gallbladder polyps characterized by thickened mucosa with invaginations into the muscularis propria?

A

Adenomyomatosis

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14
Q

Patients with gallbladder polyps under 1 cm - surveillance?

A

Ultrasound every 6-12 months

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15
Q

Risk factors for Cholangiocarcinoma: genetic conditions? Anatomic conditions? Inflammatory diseases? Infection?

A

Lynch syndrome

Choledochal cyst types 1,4,5 (Caroli disease)

PSC

Hepatitis C, liver flukes (clonorchis, opisthorchis)

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16
Q

Most sensitive test for cholangiocarcinoma?

Least sensitive?

A

Cholangioscopy and targeted biopsy

Retrieved stent cytology

17
Q

Surgical treatment for cholangiocarcinoma?

A

Whipple for distal cholangiocarcinoma

Local bile duct resection and segmental hepatectomy for proximal/perihilar tumors

18
Q

Chemotherapy for cholangiocarcinoma?

A

Gemcitabine and cisplatin