Large Intestine function Flashcards

1
Q

Describe the muscular structures of the Large Intestine?

A

Circular muscle complete

Longitudinal muscle incomplete

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2
Q

What are Haustra?

A

Pouches of the large intestine

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3
Q

What are teniae coli?

A

Bands running the length of the colon

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4
Q

What is the function of crypts in the Large intestine?

A

Lubrication for faecal movement

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5
Q

How does the rectum differ from the anal canal?

A

Muscularis thicker in canal

Simple columnar becomes stratified squamous

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6
Q

How do the internal and external anal sphincter differ?

A

External anal sphincter is skeletal muscle

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7
Q

What is the function of the colon?

A

Osmotic absorption of water to dehydrate chyme

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8
Q

What is the benefit of colonic microflora?

A

Cellulase - breakdown of undigested carbohydrate

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9
Q

What nutrient is absorbed in the colon?

A

Short chain fatty acids

Vitamin K

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10
Q

What gases make up flatus?

A
Nitrogen
CO2
Hydrogen
Methan
Hydrogen sulphide
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11
Q

Mass movement of faecal material into the rectum triggers what?

A

Mechanoreceptor activity –> defection reflex

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12
Q

Which nerves control the defecation reflex?

A

Pelvic splanchnic nerves (parasympathetic)

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13
Q

The defecation reflex causes what?

A

Contraction of the rectum
Relaxed internal anal sphincter
Contracted external
Increased colonic peristalsis

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14
Q

What are the symptoms of constipation?

A

Headaches
Nausea
Loss of appetite
Abdominal distension

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15
Q

Diarrhoea is responsible for what proportion of deaths <5y/o?

A

25% (1.5m p.a.)

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16
Q

Which bacteria cause diarrhoea?

A

Enterotoxigenic bact.
(Vibrio cholerae
Escherichia coli)

17
Q

How do enterotoxigenic bacteria cause diarrhoea?

A

Enterotoxins produced by bacteria maximally turn on crypt cell Cl- secretion

18
Q

What do enterotoxins act on?

A

Intracellular second messengers

cAMP, cGMP, Ca+

19
Q

How much water is secreted a day in cholera?

A

25L/day

20
Q

What is the treatment of secretory diarrhoea?

A

Oral rehydration therapy with Glucose/Sodium solution