Laboratory: ESR and Hematocrit Flashcards

1
Q

Normal red cells settle faster at the bottom of the tube because of their negatively charged cell surface. True or False?

A

False

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2
Q

What is the standard method for ESR?

A

Westergren

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3
Q

It is performed in the laboratory by placing anticoagulated blood in an upright tube and measures the rate of sedimentation.

A

ESR

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4
Q

A high sedimentation rate signals high levels of inflammation in the body. True or False?

A

True

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5
Q

Inflammation causes a/ an _____ fibrinogen in the plasma.

Increased
Decreased

A

Increased

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6
Q

Which of the following conditions has increased ESR?

Anemia

Increased albumin

Tilting of the tube

Sickle cells

A

Anemia
Tilting of tube

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7
Q

Patient name: Juan Dela Cruz, Sex: Male, Hematocrit= 30%. What is the interpretation?

Increased hematocrit

Decreased hematocrit

Within the normal range

A

Decreased hematocrit

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8
Q

Which side of the Wintrobe tube is used in measuring packed cell volume?

100 at the top, 0 at the bottom

0 at the top, 100 at the bottom

A

100 at the top, 0 at the bottom

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9
Q

Trapped plasma would result in _____.

Increased hematocrit

Decreased hematocrit

A

Increased hematocrit

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10
Q

A phase of ESR where red cells have rapid, and constant rate of sedimentation?

Lag phase

Decantation phase

Packing phase

A

Decantation phase

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11
Q

Which of the following conditions has a decreased hematocrit?

Dehydration

Anemia

Pregnancy

Newborns

A

Anemia

Pregnancy

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12
Q

Why increased rouleaux formation contributes to high ESR?

A

Stack of red cells become heavier, thus, it sediment faster

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13
Q

The coulter counter series of analyzers provide a direct measurement of hematocrit. True or False?

A

False

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14
Q

Buffy coat is included in the measurement of packed cell volume. True or False?

A

False

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15
Q

A marker for inflammation.

ESR

CRP

Both

Neither

A

Both

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16
Q

Two methods that can measure PCV

A

Micromethod (Microhematocrit)
Macromethod (Wintrobe’s)

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17
Q

The coulter counter series of analyzers provide a direct
measurement of hematocrit. True or False?

A

False

Rationale: Indirect measurement is measured

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18
Q

Microhematocrit: Centrifuge for __ at __.

A

5 minutes
10,000 rpm

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19
Q

Normal range of newborn hematocrit

A

53-65%

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20
Q

Normal range of infant hematocrit

A

30-43%

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21
Q

Normal range of adult male hematocrit

A

42-52%

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22
Q

Normal range of adult female hematocrit

A

37-47%

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23
Q

Incomplete sealing of the capillary tubes will give
_ results

A

Falsely-low

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24
Q

Shortened spin time or slowed centrifugation speed
may yield _ results

A

Falsely-elevated

25
Overly anticoagulated blood will be _ due to the _
Falsely-low Shrinkage of RBCs
26
The hematocrit is usually three times the hemoglobin. True or False?
True
27
Anemia and pregnancy can yield _ results of hematocrit
Decreased
28
Newborns, high altitude, dehydration and burn patients can yield _ results of hematocrit
Increased
29
Usage of macrohematocrit: Higher percentage of trapped plasma which will yield to inaccurate results. True or False?
True
30
This method is called _ since it requires more blood sample.
Macrohematocrit
31
ESR is reported as
mm/hour
32
When an inflammation process is present, the high proportion of __
Fibrinogen
33
Alteration in shapes of RBC can cause _ sedimentation rate
Decreased
34
In polycythemia, in which the RBCs are high, the ESR is generally normal. True or False?
True
35
Increased in the concentration of acute phase protein due to tissue injury will _ Rouleaux formation and hence the ESR
Increase
36
Increased plasma albumin increased the sedimentation of RBCs. True or False?
False Rationale: It retards or lowers ESR
37
Increase red cell mass will retard the sedimentation rate. True or False?
True
38
A tilt of 3 degrees in Wintrobe tube can cause errors up to 75%. True or False?
False Rationale: 3 degrees tilt causes errors up to 30%
39
Increase in room temperature may _ the sedimentation rate
Increase
40
RBCs may repel each other due to _
Negative charge on their surfaces
41
Increased Rouleaux formation contributes to high ESR. True or False?F
True
42
How many minutes does it take to complete the phase of rapid RBC falling?
40 minutes
43
ESR values tend to decrease with age and are generally lower in women. True or False?
False Rationale: ESR tends to rise with age and is higher in women
44
ESR is elevated in the black population and those with anemia. True or False?
True
45
Reference range in Westergren Method for adult female
0-15mm/hour
46
Reference range in Westergren Method for adult male
0-10mm/hour
47
Reference range in Westergren Method for children less than 10yrs
0-10mm/hour
48
Anticoagulant used in ESR
3.8% Tri-sodium citrate solution
49
Westergren pipette is closed at one end. True or False?
False Rationale: It is open at both ends. Wintrobe is closed at one end
50
Level of ESR of these conditions? Multiple myeloma Connective tissue Autoimmune diseases Tuberculosis Malignancies Severe anemia
Increased ESR
51
Level of ESR of these conditions? Polycythemia Severe leukocytosis Sickle cell disease Hereditary spherocytosis Congestive cardiac failure Corticosteroid use
Decreased ESR
52
Aspirin, Cortisone, and Quinine may _ ESR result
Decrease
53
Dextran, Methyldopa (Aldomet), Oral contraceptives, Penicillamine, Procainamide, Theophylline, and Vitamin A can cause _ ESR
Increased
54
If the concentration of EDTA is greater than recommended, the ESR will be _
Falsely-low
55
If the ESR stands for more than 60 minutes, the result will be _
Falsely-elevated
56
If the test is timed for less than 60 minutes, the result will be _.
Invalidly low
57
ESR has _ sensitivity and _ specificity
High Low
58
CRP is not affected by as many other factors as is ESR, making it a better marker of inflammation. True or False?
True