Lab Values Flashcards
Respiratory Rate Rhythm and Pattern
- Interpretation
- Newborn: 33-45
- 1 year: 25-35
- 10 years: 15-20
- Adult: 12-20
- Rhythm
- normal: Inspiration:Expiration = 1:2
- COPD: I:E = 1:3 , 1:4
ABGs: SpO2
Normal: 98-100%
High: n/a
Low: below 88-90% requires supplemental O2
ABGs: PaO2
Normal: 90-100 mmHg
High: in hyperoxygenation
Low: in cardiac decompensation, COPD, some NMS
PT: n/a
ABGs: PaCO2
Normal: 35-45 mmHg
High: in COPD, hypoventilation
Low: hyperventilation, pregnancy, PE and anxiety
ABGs: pH, whole blood
Normal: 7.35-7.45 (< acid, > alkaline)
High:
- respiratory alkalosis: hyperventilation, sepsis, liver disease, fever
- metabolic alkalosis: vomiting, potassium depletion, diuretics, volume depletion
Low:
- respiratory acidosis: hypoventilation, COPD, respiratory depressants, myasthenia
- metabolic acidosis: bicarbonate deficit, increased acids (diabetes, alcohol, starvation); renal failure , increased acid intake and loss of alkaline fluids
Hemostasis: Prothrombin Time (PT)
Normal: 11-15 sec
High: factor X deficiency, hemorrhagic dx, cirrhosis, hepatitis drugs (warfarin)
Hemostasis: Partial Thromboplastin Time (PTT)
Normal: 25-40 sec
High: Factor VII, IX, X deficiency
Hemostasis: INR
Normal: .9-1.1
- Target INR 2-3 = DVT, PE, Mechanical valves, A-fib
- Target INR 3.5 = pts with clotting disorders
PT: look for active signs of bleeding when treating patients and use compensatory training to reduce fall risk
Bleeding Time and C-reactive protein (CRP) <10mg/L
Bleeding Time 2-10 min
C-reactive protein (CRP) <10mg/L
High: platelet disorders, thrombocytopenia, high levels associated with increased risk atherosclerosis
>100 mg/L associated with inflammation and infection
CBC: White Blood Cells WBCs
Normal: 4300-10800 cells/mm3 - indicative of immune system
High: infection (all kinds), inflammation, hematologic malignancy, leukemia, lymphoma, drugs (corticosteroids)
Low: aplastic anemia, B12 or folate deficiency
PT: consider metabolic demands in presence of fever and use of mask when WBCs <1000-2000 or ANC <500-1000
Exercise Guidelines: WBC Count
4800-10,800 cells/mm3 = Normal exercise
> 5,000 = light or regular exercise
< 5,000 +Fever = no exercise
CBC: Red Blood Cells RBCs
Normal:
- male: 4.6-6.2
- women: 4.2-5.9 x106/uL
High: polycythemia
Low: anemia
CBC: Erythrocyte Sedimentation Rate ESR
Normal:
- male <15
- women< 20 mm/hr
High: infection and inflammation: rheumatic or pelvic inflammatory dx, osteomyelitis - used to monitor treatment; e.g. RA, SLE, Hodgkins Dx
CBC: Hematocrit %
Normal:
- male: 45-52%
- female: 37-48%
High: erythrocytosis, dehydration, shock
Low: severe anemia, acute hemmorhage
PT: can cause decreased exercise tolerance and increased fatigue, tachycardia
Exercise Guidelines: HCT %RBC whole blood
Men = 45-52%, women = 37-48% = Normal Exercise
>25% light or regular exercise
CBC: Hemoglobin Hgb
Normal:
- male: 13-18 g/dL
- women: 12-16 g/dL
High: polycythemia, dehydration, shock
Low: anemia, prolonged hemmorhage, RBC destruction (cancer, sickle cell)
PT: can cause decreased exercise tolerance and increased fatigue, tachnycardia
Exercise Guidelines: HgB
men = 13-18, women = 12-16 g/dL = normal unrestricted
>10 regular exercise
8-10 = light exercise
_< 8 = no exercise _
CBC: Platelet Count
Normal: 150,000-450,000 cells/mm3
High: chronic leukemia, hemoconcentration
Low: thrombocytopenia, acute leukemia, aplastic anemia, cancer chemo,
PT: increased risk of bleeding with low levels so monitor for hematuria, petechiae and other signs
- <20k = AROM, ADLs only
- 20-30k = light exercise only
- 30-50k = moderate exercise
Exercise Guidelines: Platelet Count
150,000-450,000 = normal, unrestricted
50,000-150,000 = some limitations
30,000-50,000 = moderate exercise
20,000-30,000 = light exercise
< 20,000 = ROM, ADLs, walking w/ physician approval
Pre-Albumin
20-40 mg/dL
2-day half life (short term gauge of nutrition)
<15 mg.dL = malnutrition
Albumin
3.5-5.5 g/dL
18-20 day half life (long term gauge nutrition)
<3.5 = malnurished
Creatinine
Normal: _ 115-125 mL/min _
measures GFR as a measure of renal function, regulated by arterial blood pressure and renal blood flow
BUN
Normal:
is urea produced in the liver as a by-product of protein metabolism that is eliminated by the kidneys
- elevated with increased protein intake, GI bleeding and dehydration*
- BUN-creatinine ratio is abnormal in liver disease
Glucose Levels
70-115 mg/dL (Fasting)
Short term management of diabetes
Glycosylated Hemoglobin Levels (HbA1C)
4-6%
long term management of diabetes
Hypokalemia
- low potassium
- causes:
- deficient potassium
- excessive loss from diarrhea, vommiting
- metabolic acidosis
- renal tubular disease
- alkalosis
- observe:
- ms weakness
- fatigue
- cardiac arrhythmias
- abdominal distention
- nausea/vommiting
Hyperkalemia
- high potassium
- causes
- inadequate secretion w/ acute RF
- kidney disease
- metabolic acidosis
- diabetic ketoacidosis
- sickle cell anemia
- SLE
- observe:
- symptomless until very high levels
- ms weakness
- arrhythmias
- ECG changes (tall T wave, prolonged PR & QRS)
Hyponatremia
- low sodium
- causes
- water intoxication (extracellular water)
- excess ADH
- observe:
- confusion
- decreased mental alertness to convulsions
- signs of high ICP
- poor motor coordination
- sleepiness
- anorexia
Hypernatremia
- high sodium
- causes
- water deficits (not salt excess) dehydration
- insufficient water intake
- observe
- circulatory congestion
- pulmonary edema w/ dyspnea
- HTN
- tachycardia
- agitation
- restlessness
- convulsions
hypocalcemia
- low calcium
- reduced albumin levels
- hyperphosphatemia
- hypoparathyroidism
- malabsorption of Ca or Vit D
- alkalosis
- acute pancreatitis
- vit D deficiency
- observe:
- muscle cramps
- tetany
- spasms
- parasthesias
- anxiety
- irritability
- twitching
- convulsions
- arrhythmias
- hypotension
hypercalcemia
- high calcium
- hyperparathyroidism
- tumors
- hyperthyroidism
- vit A intoxication
- observe
- fatigue
- depression
- mental confusion
- nausea/vommiting
- increased urination
- occasional cardiac arrhythmias
hypomagnesemia
- low magnesium
- hemodialysis
- blood transfusions
- chronic renal disease
- hepatic cirrhosis (alcoholism)
- chronic pancreatitis
- hypoparathyroidism
- malabsorption syndromes
- severe burns
- excessive loss of body fluids
- Observe
- hyperirritability
- confusion
- leg and foot cramps
hypermagnesemia
- high magnesium
- renal failure
- diabetic acidosis
- hypothyroidism
- Addison’s Dx
- dehydration
- use of antacids
- Observe:
- hyporeflexia
- muscle weakness
- drowsiness
- lethargy
- confusion
- bradycardia
- hypotension
Normal Urine Sample
Color
Clarity
Specific Gravity
pH
Protein
Sugar
- Color - yellow-amber
- Clarity - clear
- Specific Gravity - 1.010-1.025
- pH - 4.6-8.0 (6 avg)
- Protein - 0.8 mg/dL
- Sugar - none
Cardiac Biomarkers
Enzymes in blood stream after MI.
- creatine phosphokinase (CK-MB)
- appears ~4 hrs after infarction
- peaks 12-24 hrs
- declines over 48-72 hrs
- troponin protein (T-1)
- remains elevated for 5-7 days