Lab test 2: 29 Flashcards
Blood volume of an average adult male
5-6
Blood volume of an average adult female
4-5
What determines whether blood is bright red or dull brick red
The amount of O2 it is carrying. The more O2, the brighter the color
Most numerous leukocyte
Neutrophil
granulocytes
Neutrophil, eosinophil, basophil
also called erythrocyte
RBC
Actively phagocytotic leukocytes
Neutrophil and monocytes
Agranuloyctes
lymphocyte, monocyte
Precursor cell for platelets
Megakaryocyte
a through g are examples of
Formed elements
Number rises during parasite infections
Eosinophil
Releases histamine
Basophil
Lymphocyte
many formed in lymphoid tissue
Transports oxygen
RBC
Primarily water
Plasma
Increases in number during prolonged infection
Monocyte
Five types of WBC
Neutrophil, eosinophil, basophil, leukocyte, monocyte
Four classes of nutrients found in plasma
Amino acids, glucose, vitamins, fatty acids
Name two gases
Carbon dioxide and oxygen
Name three ions
Sodium, Potassium, Calcium
Describe consistancy and color of plasma
Slippery gelatinous fluid, straw like color (yellow)
Average life span of a red blood cell? How does anucleate affect life span
100-120 days. Cannot reproduce or repair itself
Eosinophils percent and structure
2-4%
bilobe nucleus, large cytoplasmic granules
Neutrophils percent and structure
50-70%
nucleus consists of 3-6 lobes
Lymphocytes percent and structure
25%
Spherical nucleus
Thin blue rim around nucleus
Basophils percent and structure
less than 1%
U or S shaped nuecleus
Monocytes percent and structure
3-8%
kidney shaped nucleus
Abnormal increase in number of WBC
leukocytosis
Abnormal increase in number of RBC
polycythemia
Condition of too few RBC
Anemia
Abnormal decrease in number of WBC
Leukopenia
Why are hematologic studies of blood so important
Blood composition reflects health status
Total WBC count
Normal values:
High:
Low:
Normal: 5,000-10,000 UL of blood
High: leukocytes
Low: leukopenia
Total RBC count
Normal:
High:
Low:
Normal: 4.2-6.2 million UL of blood
High: Erythrocytosis
Low: Anemia
Hematocrit
Normal:
High:
Low:
Normal: 47 plus or minus 7
High: Erythrocytosis
Low: Anemia
Hemoglobin determination
Normal:
High:
Low:
Normal: 14-18 G/ml of blood
High: Erythrocyosis
Low: Anemia
Bleeding time
Normal:
High:
Low:
Normal: 2-7 min (IV), 3-5 (duke)
High: clotting disorder
Low: vonwillebrand disease
Coagulation time
Normal:
High:
Low:
Normal: 2-6 min
High: clotting decreased
Low: clotting increased
Why is differential WBC count more valuable than total WBC count
Because any abnormal count of any WBC can indicate a problem or the source of pathology
Name given to the process of RBC production
Erythropoiesis
Hormone that acts as a stimulus for this process (RBC production)
Glycoprotein
Why might pateints with kidney disease suffer from anemia
Because it is the kidneys that release erythropoitein to stimulate bone marrow to produce RBC. If the kidneys werent functioning correctly, RBC would be reduced causing anemia
How can patients with anemia be treated
Iron supplements
Long term effect of athletic training
Enlarges your blood volume resulting in a lower RBC per unit. Known as sports anemia
a permanent move from sea level to a high altitude area
any prolonged period of oxygen deprivation results in increased RBC levels
Hematocrit
packed cell volume, occupied by erythrocytes
If you had a high hematocrit, would you expect your hemoglobin to be high or low
High. The more erythrocytes you have, the more hemoglobin needed for oxygen bonding
Anticoagulate
Agent that prevents coagulation
Two anticoagulants
Heparin and EDTA
Natural anticoagulant
Heparin
What blood type if blood clotted with A serum and B serum
AB
To what ABO groups could AB give blood
AB
From which ABO gorups could Ab recieve blood
All
Which blood type is most common
O
Least common blood type
AB
Blood type that is the universal donor
O
Why is O a universal donor
No antigens
Blood type of Mr. Adams
O
Blood type of Mr. Calhoon
A
Why does Rh negative person not have transfusion reaction first time but does second
Rh antigens of the donor sensitizes the recipient the first time. The second time it does not
What happens when ABO blood type is mismatched for the first time
Antibodies bind together causing blood to clump up and not work properly
Macrocytic hypochronic anemia
RBC larger than normal
Mycrocytic hypochronic anemia
smaller than average RBC. Pink color from low hemoglobin
Sickle cell anemia
Look like they have a C shape. Deformed RBC
Lymphcytic leukemia (chronic)
cells are a lot larger, membrane large and misshaped
Eosinophils
larger than RBC, round, membrane bilobed
Iron deficient anemia
Microcytic hypochronic anemia
a type of bone marrow cancer
Lymphocytic leukemia (chronic)
Genetic defect that causes hemoglobin to become sharp
Sickle cell
Lack of vitamin B12
Macrocytic hypochronic anemia
a tapeworm infectation
Eosinophilia
a bleeding ulcer
Sickle cell anemia
Relationship between cholesterol, hypertension, heart attacks and strokes
Chloresterol is a component of smooth muscle plaques. Plaques narrow arteries (hypertension). They also form blood clots that block smaller vessels (heart attacks and strokes)