lab male repro Flashcards
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layers of testes
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. tunica albuginea
2. blood vessels
3. septum
4. tseminiferous tubules
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seminiferous tubules with myoepithelial cells, 2 seminiferous tubules; cells in the base are spermatogoonia (A nd B etc), primary spermatocytes, condensed chromatine early spermatids, alargados son los late spermatid, celulas largas son sertoli
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early spermatids, primary spermatids, myoepithelial cells, espermatogoonia, late spermatids, sertoli cells
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- spermatogonia
- primary spermatids
- early spermatids
- sertoli cells
- late spermatids
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late spermatid; histones have been replaces by promatines; intercellulr junctions to keep it attached to sertoli
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sertoli-to-sertoli blood-testis barrier; dividion de lumunal compartment and basal compartment.
microfilaments arrows, endoplasmic reticulum, tught junctions, celulas haploides
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leydig cells (interstitial cells) producen testosterona; most abundand SER; mitocondria ocn crrestas
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leydig cells (interstitial cells) producen testosterona; most abundand SER; mitocondria ocn crrestas
a.ST=Seminiferous tubules
b. IC=interstitial (Leydig) cells
c,d,e = Sertoli cells stained with antibody to prosaposin (intracelular controlan actividad d elysosoma y extracellular es neuroprotectora)
Sertoli cells possess receptors for testosterone and FSH
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Leydig (Interstitial) Cells testosterone for spermatogeesis
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Leydig (Interstitial) Cells
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Leydig Cell –steroid secreting cells
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Crystal of Reinke
what is cryptochidism?
Failure of testis to descend, occurs in 45 male neonates. Causes infertility, must be surgically corrected 2-3years old.
what is testicular cancer?
Interstitial and Sertoli cells tumors are rare. (95%) are germ cell tumors that appear after puberty. Seminoma is a malignant germ cell tumor.
describe male infertility
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Decreased semen quality is a major cause of male infertility. Oligospermia: low sperm count less than 15million/ml
Azoospermia: no sperm in ejaculate
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Abnormal sperm morphology and flagellar defects (PrimaryciliarydyskinesiaPCD)
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Spermiation failure: spermatidsare notreleased, are retainedand phagocytosedbythe Sertoli cell.
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Intratesticular Genital Ducts – Tubuli Recti and Rete Testis. sertoli cells in arrow and goes to tubules recti and rete testis
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Tubuli Recti (Straight tubules) and Rete Testis, sertoli cells arrow, simple cuboinal rete testis
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rete testis
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efferent ductules, columnar ciliated and cuboidal non ciliated
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Efferent ductules Pseudostratified columnar epithelium: Clumps of tall and short cells, sawtooth appearance.
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efferent ductules
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fferent ductules
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efferent ductules
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Efferent Ductules and Head of Epididymis
(mas cercana a los ductules es el head of epididymis)
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lumen vacio, stereociia, head of epididymis
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stereocilia con actina, head of epididymis
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se acumula el sperm, columnares, mad musculo liso, epididymis tail
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Epididymis tail
Epithelium pseudostratified with stereocilia
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Epididymis tail
Epithelium pseudostratified with stereocilia. solos las tall columnar contactan region apical; abas celulas contcatan la base.
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Epididymis head
Epithelium pseudostratified with stereocilia
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Ductus Deferens (Vas Deferens)
Pseudostratified columnar epithelium stereocilia
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Ductus Deferens (Vas Deferens)
Pseudostratified columnar epithelium stereocilia
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seminal vesicle; pseudostratified epithelium
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seminal vesicle; pseudostratified epithelium
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seminla vesicle; smooth muscle, projections
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bottom: seminal vesicle
top: corpora amylacea+prostatic concretions (porostate)
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orpora amylacea+prostatic concretions (porostate)
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corpora amylacea+prostatic concretions (porostate); smooth muscl ein stroma; pseudotstratified
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uret
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penis, spongy an dcavernosum
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penis- erectile tissue
right: lleno de sangre, cuadrado es penile urehtra
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penile urethra
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penile ur; glands of littre to lubricate penile urethra;
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head of epididymis
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seminla vesicle
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Benign Prostatic Hypertrophy
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Cryptorchidism: Testis of a post pubertal patient demonstrating the absence of spermatogenesis in the seminiferous tubule as well as a very thick, hyalinized basement membrane.
sertoli cells
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cryptochidism; sertoli
