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Lab 6 Structures Flashcards

1
Q

label

A
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2
Q

medial division fibers

A
  • large fiber afferents
  • heavily myelinated
  • vibration, joint position sense, discriminative touch
  • enters spinal cord through dorsal white matter funiculus
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3
Q

lateral division fibers

A
  • small fiber afferents
  • lightly/non-myelinated
  • pain/temperature
  • enters spinal cord via Lissauer’s tract and then dorsal horn gray matter
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4
Q

what are the 2 ascending sensory tracts that are 3 neuron pathways?

A
  • dorsal column medial lemniscal tract (DCML)
  • spinothalamic tract (SPTH) contained within anterolateral system (ALS)
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5
Q

what is the function of the dorsal column medial lemniscal tract?

A

carries ascending somatosensory info regarding vibration, joint position, discriminative touch from body to cerebral cortex

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6
Q

origin of 1st ordered neuron

DCML

A

periphery sensory receptors (Merkel disc, Pacinian corpuscle, Meissner corpuscle)

pseudo-unipolar

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7
Q

division of dorsal root for 1st ordered neuron

DCML

A

medial

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8
Q

where does 1st ordered neuron enter spinal cord?

DCML

A

dorsal white matter

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9
Q

where does 1st ordered neuron travel?

DCML

A
  • ascends via dorsal columns
  • gracile fasciculi (LE is medial)
  • cuneate fasciculi (UE is lateral)
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10
Q

where does 1st ordered neuron synapse?

DCML

A
  • synapses in dorsal column nuclei
  • gracile/cuneate tubercles in caudal medulla
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11
Q

origin of 2nd ordered neuron

DCML

A

dorsal column nuclei (gracile/cuneate tubercles)

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12
Q

where does 2nd ordered neuron travel?

DCML

A

crosses at level of nuclei and ascends as combined bundles of white matter fibers (medial lemniscus) to thalamus

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13
Q

where does 2nd ordered neuron synapse?

DCML

A

synapses in ventral posterior lateral (VPL) nucleus of thalamus

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14
Q

origin of 3rd ordered neuron

DCML

A

VPL of thalamus

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15
Q

where does 3rd ordered neuron travel?

DCML

A
  • exits VPL of thalamus
  • enters posterior limb of internal capsule
  • travels to cerebral white matter
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16
Q

where does 3rd ordered neuron synapse?

DCML

A

terminates in cerebral cortex (post central gyrus)

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17
Q

what is the function of the spinothalamic tract?

A

carries ascending sensory info regarding pain/temperature from body to cerebral cortex

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18
Q

origin of 1st ordered neuron

SPTH

A

peripheral sensory receptors (nociceptors)

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19
Q

division of dorsal root for 1st ordered neuron

SPTH

A

lateral

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20
Q

where does 1st ordered neuron enter spinal cord?

SPTH

A
  • Lissauer’s tract
  • ascends 1-2 levels
  • synapses in gray matter of dorsal horn of spinal cord
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21
Q

where does 1st ordered neuron travel?

SPTH

A

ascends 1-2 levels within Lissauer’s tract before entering spinal cord gray matter to synapse

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22
Q

where does 1st ordered neuron synapse?

SPTH

A

synapses in gray matter of dorsal horn of spinal cord

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23
Q

origin of 2nd ordered neuron

SPTH

A

dorsal horn gray matter of spinal cord

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24
Q

where does 2nd ordered neuron travel?

SPTH

A

crosses spinal cord via ventral white commissure to join contralateral white matter bundle (ALS/SPTH) and then ascends to VPL of thalamus

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25
Q

where does 2nd ordered neuron synapse?

SPTH

A

synapses in VPL of thalamus

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26
Q

origin of 3rd ordered neuron

SPTH

A

VPL of thalamus

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27
Q

where does 3rd ordered neuron travel?

SPTH

A

exits VPL of thalamus and enters posterior limb of internal capsule and ascends to cerebral white matter

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28
Q

where does 3rd ordered neuron synapse?

SPTH

A

terminates in cerebral cortex (post central gyrus) and widespread cortical areas

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29
Q

what are the 3 ascending sensory tracts that are 2 neuron pathways?

A
  • dorsal spinocerebellar tract (DSCT)
  • cuneocerebellar tract (CCT)
  • ventral spinocerebellar tract (VSCT)
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30
Q

what is the function of the dorsal spinocerebellar tract?

A

muscle spindle info about LE

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31
Q

origin of 1st ordered neuron

DSCT

A

muscle spindles of trunk/LE

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32
Q

division of dorsal root for 1st ordered neuron

DSCT

A

medial

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33
Q

where does 1st ordered neuron enter spinal cord?

DSCT

A

dorsal white matter of spinal cord

34
Q

where does 1st ordered neuron travel?

DSCT

A
  • travels ventrally towards intermediate gray of spinal cord
  • Clarke’s nucleus (T1-L3 segments)
35
Q

where does 1st ordered neuron synapse?

DSCT

A

synapses in Clarke’s nucleus in intermediate gray of spinal cord

36
Q

origin of 2nd ordered neuron

DSCT

A

Clarke’s nucleus

37
Q

where does 2nd ordered nucleus travel?

DSCT

A
  • exits nucleus and moves laterally to dorsolateral perimeter of ipsilateral spinal cord white matter to ascend as fiber bundle called DSCT
  • ascends to inferior cerebellar peduncle
38
Q

where does 2nd ordered nucleus synapse?

DSCT

A

enters inferior cerebellar peduncle to terminate in ipsilateral cerebellum

39
Q

what is the function of the cuneocerebellar tract?

A

non-conscious information from UE/trunk

40
Q

origin of 1st ordered neuron

CuCT

A

muscle spindles of UE/upper trunk

41
Q

division of dorsal root for 1st ordered neuron

CuCT

42
Q

where doest 1st ordered neuron enter spinal cord?

CuCT

A

dorsal white matter of spinal cord

43
Q

where does 1st ordered neuron travel?

CuCT

A
  • enters lateral aspect of spinal cord and immediately ascends as white matter bundle lateral to cuneate fasciculus
  • ascends to lower medulla and enters accessory (lateral) cuneate nucleus
44
Q

where does 1st ordered neuron synapse?

CuCT

A

synapses in accessory cuneate nucleus (ipsilateral)

45
Q

origin of 2nd ordered neuron

CuCT

A

accessory cuneate nucleus

46
Q

where does 2nd ordered neuron travel?

CuCT

A

exits nucleus and ascends to inferior cerebellar peduncle

47
Q

where does 2nd ordered neuron synapse?

CuCT

A

terminates in ipsilateral cerebellum

48
Q

what is the function of the ventral spinocerebellar tract?

A

nonconscious information whole limb/body

49
Q

origin of 1st ordered neuron

VSCT

50
Q

division of dorsal root for 1st ordered neuron

VSCT

51
Q

where does 1st ordered neuron enter spinal cord?

VSCT

A

dorsal white matter of spinal cord

52
Q

where does 1st ordered neuron travel?

VSCT

A

travels ventrally to spinal border neurons in lateral region of intermediate gray of spinal cord

53
Q

where does 1st ordered neuron synapse?

VSCT

A

synapses on spinal border neurons

54
Q

origin of 2nd ordered neuron

VSCT

A

spinal border neurons of intermediate gray

55
Q

where does 2nd ordered neuron travel?

VSCT

A
  • crosses via ventral white commissure to contralateral white matter perimeter pathway (VSCT)
  • ascends to level of superior cerebellar peduncle
  • crosses again to enter cerebellum
56
Q

where does 2nd ordered neuron synapse?

VSCT

A

terminates in cerebellum (on side from where first order neuron originated)

57
Q

what is the function of the trigeminothalamic tract?

A

sensation from face travels in different pathway to cortex (post-central gyrus)

58
Q

what are the 2 subpathways of the trigeminothalamic tract?

A
  • pain/temperature pathway
  • vibration/position sense/discriminative touch pathway
59
Q

origin of 1st ordered neuron

pain/temperature of trigeminothalamic tract

A

sensory receptors of face

60
Q

location of cell body for 1st ordered neuron

pain/temperature of trigeminothalamic tract

A

trigeminal ganglion near mid/upper pons

61
Q

where does 1st ordered neuron enter brainstem?

pain/temperature of trigeminothalamic tract

A

via trigeminal nerve

62
Q

where does 1st ordered neuron travel?

pain/temperature of trigeminothalamic tract

A

enters pons and descends within spinal trigeminal tract to enter spinal trigeminal nucleus

63
Q

where does 1st ordered neuron synapse/terminate?

pain/temperature of trigeminothalamic tract

A

synapses in spinal trigeminal nucleus (which runs from mid pons to upper spinal cord)

64
Q

origin of 2nd ordered neuron

pain/temperature of trigeminothalamic tract

A

spinal trigeminal nucleus

65
Q

where does 2nd ordered neuron travel?

pain/temperature of trigeminothalamic tract

A

crosses out of nucleus and ascends in trigeminothalamic tract to VPM of thalamus

66
Q

where does 2nd ordered neuron synapse/terminate?

pain/temperature of trigeminothalamic tract

A

synapses in VPM of thalamus

67
Q

origin of 3rd ordered neuron

pain/temperature of trigeminothalamic tract

A

VPM of thalamus

68
Q

where does 3rd ordered neuron travel?

pain/temperature of trigeminothalamic tract

A
  • exits VPM to enter posterior limb of internal capsule
  • ascends through cerebral white matter
69
Q

where does 3rd ordered neuron synapse/terminate?

pain/temperature of trigeminothalamic tract

A

terminates in inferior-lateral aspect of post-central gyrus

70
Q

origin of 1st ordered neuron

vibration/position sense/discriminative touch of trigeminothalamic tract

A

sensory receptors in face

71
Q

location of cell body for 1st ordered neuron

vibration/position sense/discriminative touch of trigeminothalamic tract

A

trigeminal ganglion near mid/upper pons

72
Q

where does 1st ordered neuron enter brainstem?

vibration/position sense/discriminative touch of trigeminothalamic tract

A

via trigeminal nerve

73
Q

where does 1st ordered neuron travel?

vibration/position sense/discriminative touch of trigeminothalamic tract

A

enter pons and slightly ascends to enter ipsilateral chief/sensory nucleus of V

74
Q

where does 1st ordered neuron synapse/terminate?

vibration/position sense/discriminative touch of trigeminothalamic tract

A

synapses in ipsilateral chief/sensory nucleus of V

75
Q

origin of 2nd ordered neuron

vibration/position sense/discriminative touch of trigeminothalamic tract

A

chief/sensory nuclues of V

76
Q

where does 2nd ordered neuron travel?

vibration/position sense/discriminative touch of trigeminothalamic tract

A
  • exits nucleus and crosses to joint trigeminothalamic tact
  • ascends to VPM of thalamus
77
Q

where does 2nd ordered neuron synapse/terminate?

vibration/position sense/discriminative touch of trigeminothalamic tract

A

synapses in VPM of thalamus

78
Q

origin of 3rd ordered neuron

vibration/position sense/discriminative touch of trigeminothalamic tract

A

VPM of thalamus

79
Q

where does 3rd ordered neuron travel?

vibration/position sense/discriminative touch of trigeminothalamic tract

A
  • exits VPM to enter posterior limb of internal capsule
  • ascends through cerebral white matter
80
Q

where does 3rd ordered neuron synapse/terminate?

vibration/position sense/discriminative touch of trigeminothalamic tract

A

terminates in inferior-lateral post-central gyrus

81
Q

label ascending pathways

Neuroscience (9 decks)

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