Lab 3 - Immune System - 5

Question 1

• What is the internal defense for innate immunity?

Answer 1

Phagocytic cells, natural killer cells, antimicrobial cells, inflammatory cells

Question 2

• What are B and T Cells?

Answer 2

So T cells fight INFECTED cells and B cells fight INVADERS outside the cell

Question 3

• What is an Antigen?

Answer 3

A substance that elicits a T or B cell response –so it stimulates an immune response

Question 4

• What is molecular recognition?

Answer 4

Essentially it is the binding of molecules to foreign cells and viruses

Note: (I believe this is the same thing as Receptors - since they bind to foreign cells and viruses but also - they play a role in signaling/responsible for inflammation response, local containment of infection, etc)

Question 5

• When it comes to Receptor Molecules, how does activation of defense respond?

Answer 5

By way of utilizing TLRs when a pathogen is present so in a sense, this causes an innate immunity response – possibly adaptive as well

Question 6

• What is TLR or Toll-like Receptor?

Answer 6

Within Innate Immunity - binds to fragments of molecules characteristic of a set of pathogens

Also - they recognize molecules derived from microbes

Question 7

• So when there is a pathogen present such as a virus or fungi which has Lipopolysaccharide, flagellin, CpG DNA and double-stranded RNA, what kind of response factor does this trigger?

Answer 7

TLR Proteins trigger internal innate immunity response