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Immune system > L5 > Flashcards

L5 Flashcards

1
Q

Where does DC take antigens?

A

to lymph nodes

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2
Q

Function of Cytotoxic T cells?

A

Kills virus infected cells and cancer cells

kills (sick cells)

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3
Q

DC phagocytose and converts antigens to?

A

peptides

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4
Q

What does DC do with peptides?

A

Present peptides on MHC to other white blood cells, T cells

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5
Q

What is an activated B cell? and what does it do?

A

Plasma cells actively secrete antibodies

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6
Q

What does CD4 T cells do?

A

Help B cells make antibodies

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7
Q

What does CD8 T cells do?

A

Become cytotoxic and kills virus infected and cancer cells

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8
Q

How does endogenous antigens and MHC-I work?

A

Cytoplasmic antigen within cells get broken down and their peptides are displayed on MHC-I showing they are infected

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9
Q

How is MHC-I antigen processing happen?

A

Antigenic proteins are degraded into peptides in cytoplasm

peptides imported to endoplasmic reticulum

Peptide is loaded onto MHC-I in ER

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10
Q

How is MCH-II antigen processing happen?

A

antigenic proteins degraded in phagolysosome in

Peptide loading of MHC-II takes place in phagolysosome

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Immune system (9 decks)

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