L4

Question 1

How does activated dentritic communication with T cells happen?

Answer 1

-Dendritic cells make cytokines which bind to receptors on T cell membranes

-Dendrites have cell surface receptors which bind directly to T cell ligand

-Present antigen to receptors on T cells

Question 2

What is the function of MHC?

Answer 2

on dendritic cells which presents antigen to T cells

Question 3

What is MHC-I and its expressed on?

Answer 3

Presents endogenous (intracellular) antigen

expressed on all nucleated cells

Question 4

What is MHC-II? and its expressed on?

Answer 4

Presents exogenous (extracellular) antigen

expressed only on antigen presenting cells eg dendritic cells

Question 5

What are cytokines?

Answer 5

Molecules eg interleukins and interferons which control growth and activity of immune cells

Question 6

What are chemokines?

Answer 6

Molecules which stimulate cell migration

Question 7

Where are cytokines and chemokines produced?

Answer 7

By innate and adaptive immune cells and cells that influence immune system eg epithelial

Question 8

What is the function of helper T cells?

Answer 8

Activates B cell, helping it make antibodies

Making cytokines bind to receptors on B cell membranes

Have cell surface receptors that bind to a B cell ligand

Question 9

How can B ells be activated?

Answer 9

Antigen and T cells

Complement proteins

Question 10

What happens when B cells are activated?

Answer 10

Produces Antibody