L30 Muscle Tissue Flashcards

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1
Q

Sphincters are operated by what type of muscle?

A

Skeletal muscle

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2
Q

What is being described:

Non-dividing cells surrounded by satellite cells and contained in a sarcolemma.

A

Muscle fibre

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3
Q

What are muscular satellite cells?

A

Undifferentiated muscle stem cells with regenerative potential.

Function as a reserve that can be activated to replace or increase muscle, as necessary.

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4
Q

When a satellite cell is activated by injury, what happens?

A

The satellite cell undergoes asymmetric division - forming one satellite cell and one myoblast. The myoblast matures and fuses to the muscle fibre.

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5
Q

True or false: Skeletal muscle is striated

A

True

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6
Q

True or false: Skeletal muscle is controlled by the autonomic nervous system

A

False, it requires somatic or voluntary input.

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7
Q

Fused myocytes form a __1__, and are surrounded by endomysium.

Bundles of 1 form muscle fascicle, surrounded by __2__.

Bundles of 2 form muscle, surrounded by __3__.

A

1) muscle fibre
2) perimysium
3) epimysium

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8
Q

What are the myofilaments inside a muscle fibre?

A

Thin: actin, tropomyosin, troponin

Thick: myosin

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9
Q

What is a myofibril?

A

Any one of the contractile threads found in a muscle fibre.

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10
Q

What are transverse tubules (T-tubules) and what do they do?

A

‘Tunnels’ throughout muscle fibres that conduct action potentials from the sarcolemma to initiate contraction.

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11
Q

What is a sarcomere?

A

The smallest functional unit of muscle (not the smallest structural unit).

Contraction happens here.

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12
Q

What forms the I band of the sarcomere?

A

Thin bands of actin

It looks lighter because actin is isotropic

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13
Q

What forms the A bands of the sarcomere?

A

Thick bands of myosin

Anisotropic, therefore appears dark

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14
Q

What is the Z line in the sarcomere?

A

Protein chain that supports the actin filaments (I bands).

Z = zig zag

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15
Q

What is the M line in a sarcomere?

A

Consists of proteins supporting the thick myosin filaments

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16
Q

Where is the H zone on a sarcomere?

A

The central region that contains only thick filaments

17
Q

How is contraction achieved in the sarcomere?

A

Sliding of thick and thin filaments in the zone of overlap.

18
Q

True or false: Striations can be found in cardiac muscle

A

True

19
Q

Is cardiac muscle mononucleated or multinucleated?

A

Mononucleated. Cells are not fused.

20
Q

Is skeletal muscle mononucleated or multinucleated?

A

Multinucleated.

Myoblasts fuse together to form multinucleated fibres

21
Q

Cardiac muscle contains intercalated discs at the ends of the cardiocytes. What structures are found here and why?

A

Gap junctions and desmosomes allow exchange of ions and molecules - allows spread of action potentials.

22
Q

True or false: A sarcomere Z line appears zig zag shaped, and the M line appears straight

A

True

z line = zig zag

23
Q

True or false: cardiac muscle contraction is not reliant on the nervous system for stimulation.

A

True

Pacemaker cells stimulate contractions; the nervous system can only alter the rate of activity.

24
Q

True or false: Smooth muscle is incapable of regeneration

A

False.

Smooth muscle cells can divide, therefore the tissue is capable of regeneration.

25
Q

True or false: Cardiac muscle is incapable of regeneration

A

True

26
Q

In which type of muscle will you NOT find sarcomeres?

A

Smooth muscle