Histology Flashcards
Which of the following is NOT primarily composed of connective tissue?
a. Blood
b. Bone
c. Tendon
d. Intervertebral disc
e. Myometrium
e. Myometrium
The myometrium is the muscular layer of the uterus, thus it is composed of muscle tissue
Which of the following is NOT a fibre found in connective tissue?
a. Collagen fiber
b. Elastic fibre
c. Reticular fibre
d. Purkinje fibre
e. All of the above are fibres found in connective tissue
d. Purkinje fibre
There are 3 types of connective tissue fibres: collagen, elastic, and reticular.
Purkinje fibres are specialised muscle fibres found in the heart.
Which connective tissue cell type contains properties of smooth muscle cells?
a. Fibroblast
b. Myofibroblast
c. Histiocyte
d. Plasma cell
e. Mast cell
b. Myofibroblast
Myofibroblasts contain
properties of both fibroblasts and smooth muscle cells.
Fibroblasts produce the ground subtance in connective tissue. Histiocytes are macrophages. Plasma cells are derived from B lymphocytes. Mast cells secrete histamins and heparin.
Which cell is a connective tissue macrophage?
a. Kupffer cells
b. Histiocyte
c. Dust cell
d. Langerhans cell
e. Microglia
b. Histiocyte
Kupffer cells are hepatic macrophages. Dust cells are alveolar macrophages. LAngerhans cells are macrophages in the skin. Microglia and the CNS macrophages.
Which of the following can be classified as “specialised connective tissue”?
a. Mesenchyme
b. Mucous connective tissue
c. Dense connective tissue
d. Blood
e. Loose connective tissue
d. Blood
Specialised connective tissue includes cartilage, bone, adipose tissue, blood, and haemopoietic tissue, and lymphatic tissue.
Which of the following can be classified as “embryonic connective tissue”?
a. Cartilage
b. Mucous connective tissue
d. Adipose tissue
d. Bone
e. Blood
b. Mucous connective tissue
Embryonic connective tissue includes mesenchyme and mucous connective tissue.
What type of tissue makes up the dermis of the skin?
a. Mucous connective tissue
b. Mesenchyme
c. Loose irregular connective tissue
d. Dense irregular connective tissue
e. Dense regular connective tissue
d. Dense irregular connective tissue
Irregular as it needs strength in all directions.
What type of adipose tissue tends to increase as humans age?
a. Brown adipose tissue
b. White adipose tissue
c. Unilocular adipose tissue
d. Multilocular adipose tissue
e. Both b and c
e. Both b and c
Brown adipose tissue is multilocular adipose tissue. This is present during fetal development and then decreases after birth.
White adipose tissue is unilocular adipose tissue. This type of tissue persists into adulthood.
Which of the following would be best suited to differentiate collagen fibres from other fibres?
a. Wright’s stain
b. Haematoxylin and eosin stain
c. Sudan stain
d. Silver impregnation
e. Masson’s trichrome stain
e. Masson’s trichrome stain
A peripheral blood smear would be best visualised with Wright’s stain. Haematoxylin and eosin stain is the most commonly used tissue stain for routine histological examination. Lipids are best displayed with a sudan stain. Silver impregnation, such as with a reticular stain, can be used to visualise reticular fibres. Collagen fibres can be differentiated from other fibres by staining with Masson’s trichrome stain.
Which of the following is NOT primarily composed of connective tissue?
a. Bone marrow
b. Articular cartilage
c. Heart
d. Mesenchyme
e. Fat
c. Heart
Please be aware that there is connective tissue in the heart. The blood in the heart, for example, is composed of connective tissue. The pericardium is also composed of connective tissue. However, the primary tissue composing the heart is cardiac muscle.
Which one of these cells is not a cell type routinely found in loose connective tissue?
a. Fibroblast
b. Microglia
c. Histiocyte
d. Plasma cell
e. Mast cell
b. Microglia
Microglia are supporting cells in the nervous system.
Which of the following can be classified as “specialized connective tissue”?
a. Cartilage
b. Loose connective tissue
c. Mesenchyme
d. Dense connective tissue
e. Mucous connective tissue
a. Cartilage
Specialised connective tissue includes cartilage, bone, adipose tissue, blood and haemopoietic tissue, and lymphatic tissue.
Which of the following can be classified as “connective tissue proper”?
a. Adipose tissue
b. Dense irregular connective tissue
c. Bone
d. Blood
e. Cartilage
b. Dense irregular connective tissue
Connective tissue proper consists of loose irregular connective tissue and dense connective tissue (regular and irregular).
What type of tissue is Wharton’s jelly?
a. Mucous connective tissue
b. Mesenchyme
c. Loose irregular connective tissue
d. Dense irregular connective tissue
e. Dense regular connective tissue
a. Mucous connective tissue
What type of tissue is a tendon composed of?
a. Mucous connective tissue
b. Mesenchyme
c. Loose irregular connective tissue
d. Dense irregular connective tissue
e. Dense regular connective tissue
e. Dense regular connective tissue
Dense regular as it needs strength against directional force
What does connective tissue develop from?
a. Mesothelium
b. Mesenchyme
c. Mesangial cells
d. Mesentery
e. Wharton’s jelly
b. Mesenchyme
What colour do elastic fibres stain with Verhoeff Elastic stain?
a. Red/Orange
b. Pink/red
c. Purple/Red
d. Blue/black
e. Green/blue
d. Blue/black
Verhoeff Elastic stain stains elastic fibers blue/black. Collagen stains pink/red.
Which of the following is a component of the ground substance?
a. Hyaluronic acid
b. Proteoglycans
c. Glycosaminoglycans
d. Chondroitin sulfate
e. All of the above
e. All of the above
Within connective tissue, the cells and fibres are embedded in the ground substance. The ground substance is amorphous material. It is composed of proteoglycans and glycosaminoglycans. Hyaluronic acid and chondroitin sulfate are glycosaminoglycans.
Which of the following is NOT primarily composed of connective tissue?
a. Spinal cord
b. Pubic symphysis
c. Ligament
d. Areolar tissue
e. Organ capsule
a. Spinal cord
Spinal cord is composed of nervous tissue
Which connective tissue cell type produces the ground substance in connective tissue?
a. Fibroblast
b. Myofibroblast
c. Histiocyte
d. Plasma cell
e. Mast cell
a. Fibroblast
Which connective tissue cell is derived from B lymphocytes?
a. Fibroblast
b. Myofibroblast
c. Histiocyte
d. Plasma cell
e. Mast cell
d. Plasma cell
Which of the following can be classified as “specialised connective tissue”?
a. Mesenchyme
b. Bone
c. Dense connective tissue
d. Mucous connective tissue
e. Loose connective tissue
b. Bone
Specialised connective tissue includes cartilage, bone, adipose tissue, blood and haemopoietic tissue, and lymphatic tissue.
Which of the following can be classified as “connective tissue proper”?
a. Bone
b. Blood
c. Adipose tissue
d. Loose irregular connective tissue
e. Cartilage
d. Loose irregular connective tissue
What type of connective tissue is an undifferentiated tissue found in the embryo?
a. Mucous connective tissue
b. Mesenchyme
c. Loose irregular connective tissue
d. Dense irregular connective tissue
e. Dense regular connective tissue
b. Mesenchyme