L3. Sites of Haematopoiesis in a lifetime Flashcards
1
Q
What is the dominant site of haematopoiesis in a fetus at 0-2 months, 2-7 months and 5-9 months?
A
0-2 –> Yolk sac
2-7 –> Liver, spleen
5-9 –> bone marrow
2
Q
What is the dominant site of haematopoiesis in infants?
A
Bone marrow, mostly all bones
Dwindling post-parturition contribution from liver/spleen that ceases in the first few months of life
3
Q
What are the dominant sites of haematopoiesis in adults? (7)
A
Vertebrae Ribs Sternum Skull Sacrum Pelvis Proximal ends of the femur
4
Q
Which places can have haematopoiesis in adults when they’re ill?
A
In the liver and spleen, also known as extramedullary hematopoiesis.
5
Q
What is the arrangement of haematopoetic stem cells?
A
The sites lay at the edge of the bone marrow. Here, you can find adipocytes, clusters of erythrocytic cells, megakaryocytes.
