(L28- Using Antimalarials) Flashcards

1
Q

Indicate drug for:

  • Uncomplicated Malaria
  • P. falciform
  • no known resistance
A

chloroquine (hydroxychloroquine)

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2
Q

Indicate drug for:

  • Uncomplicated Malaria
  • P. falciform
  • chloroquine-resistance (or choices for unknown resistance)
A

1) Malarone = atovaquone + proguanil
2) Coartem = artemether-lumefantrine
3) quinine + doxycycline
4) mefloquine

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3
Q

Indicate drug for:

  • Uncomplicated Malaria
  • P. malariae
  • all regions (= no known resistance)
A

chloroquine (hydroxychloroquine)

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4
Q

Indicate drug for:

  • Uncomplicated Malaria
  • P. vivax, P. ovale
  • all regions (= little known resistance)
A

chloroquine (/hydroxychloroquine) + primaquine

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5
Q

Indicate drug for:

  • Uncomplicated Malaria
  • P. vivax
  • chloroquine-resistant
A

1) quinine + doxycycline + primaquine
2) Malarone (= atovaquone-proguanil) + primaquine
3) mefloquine + primaquine

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6
Q

Indicate drug for:

  • Uncomplicated Malaria in Pregnancy
  • all species of Plasmodium
  • no known resistance
A

chloroquine (hydroxychloroquine)

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7
Q

Indicate drug for:

  • Uncomplicated Malaria in Pregnancy
  • P. falciparum
  • chloroquine-resistant
A

1) mefloquine

2) quinine + clindamycin

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8
Q

Indicate drug for:

  • Uncomplicated Malaria in Pregnancy
  • P. vivax
  • chloroquine-resistant
A

mefloquine

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9
Q

Indicate drug for:

  • Uncomplicated Malaria in Pregnancy
  • P. vivax, P. ovale
  • prophylaxis
A

chloroquine

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10
Q

Indicate drug for:

  • Severe Malaria
  • all species, all regions
  • route of administration
A

1) quinidine + doxycycline/clindamycin (IV) —- with progression to quinine + doxycycline (oral)

2)
1st- artesunate
2nd- Malarone (atovaquone-proguanil) OR clindamycin OR mefloquine

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11
Q

Indicate drug for:

  • Severe Malaria in Pregnancy
  • all species of Plasmodium, all regions
  • 1st trimester
A

1) quinidine

2) artesunate

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12
Q

Indicate drug for:

  • Severe Malaria in Pregnancy
  • all species of Plasmodium, all regions
  • 2nd/3rd trimester
A

1) artesunate

2) artemether

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13
Q

Indicate drug for:

  • Malaria chemoprophylaxis
  • all species of Plasmodium, all regions
  • not a known region with resistance
A

chloroquine

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14
Q

Indicate drug for:

  • Malaria chemoprophylaxis
  • all species of Plasmodium, all regions
  • known region with chloroquine-resistance
A

1) mefloquine
2) doxycycline
3) primaquine

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15
Q

Indicate drug for:

  • Malaria chemoprophylaxis in Pregnancy
  • all species of Plasmodium, all regions
  • not a known region with resistance
A

chloroquine

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16
Q

Indicate drug for:

  • Malaria chemoprophylaxis in Pregnancy
  • all species of Plasmodium, all regions
  • known region with chloroquine-resistance
A

mefloquine