L23: Renal Histology Flashcards

1
Q

glomerulus contains

A

afferent and efferent arterioles
capillaries
juxtaglomerular cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

juxtaglomerular cells secrete ____, a _____ factor

A

renin

hypertensive factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

bowman’s capsule is a double layered dilation of the nephron w/ and inner and outer layers, called

A

parietal layer - outer

visceral layer - inner

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

outer layer of bowman’s capsule

A

simple squame

parietal layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

inner layer of bowman’s capsule

A

inner layer of podocytes in contact w/ endothelium of glomerular capillaries

visceral layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

bowman’s space

A

located between the two layers of the capsule

continuous w/ the lumen of the proximal convoluted tubule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

the renal corpuscle in involved w/ producing a

A

filtrate of blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

after the renal corpuscle, the following portions of the nephron are involved in _____ the ______ .

A

modifying the filtrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

list and 3 steps of urine formation and where they occur

A

filtration – renal corpuscle
reabsorption
secretion - both occurring in renal tubules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

intraglomerular mesangium

A

these cells are located between capillaries in glomerulus and cover endothelium not covered by podocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

extraglomerular mesangium

A

these cells are located between afferent and efferent arterioles at the vascular pole

associated w/ juxtaglomerular apparatus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

mesangium are formed by _____ cells embedded in a

A

mesangial cells

a mesangial matrix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

functions of mesangium

A
contractile
phagocytic
proliferative
synthesize matrix and collagen
secretion
support
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

mesangial cells respond to

A

angiotensin II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

list the components of the juxtaglomerular apparatus

A

macula densa
extraglomerular mesangial cells
juxtaglomerular cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

macula densa is formed by ? in the wall of ? and responds to changes in concentration of ___ and ___ in filtrate

A

densely packed cells
in walls of convoluted tubule

changes in Na and Cl conc. in filtrate

17
Q

juxtaglomerular cells are modified ____ _____ cells that secrete _____ into blood when stimulated by ____ _____.

A

smooth muscle cells
secrete renin
macula densa

18
Q

another term for renal tubule

A

uriniferous tubule

19
Q

list in order the components of the renal tubule

A
proximal convoluted tube
descending limb
loop of henle
ascending limb
distal convoluted tube
collecting duct
20
Q

renal filtration barrier slits are created by

A

pedicles of adjacent podocytes

21
Q

list substances allowed to pass thru bowman’s capsule

A

water, glucose, ions

proteins excluded
large neg. molecules excluded

22
Q

what type of cells make up the walls of the proximal tubule

A

truncated pyramidal cells

make up the simple cuboidal epi

23
Q

functions of the proximal tubule

A

reabsorb most water, Na, Cl

remove all glucose and amino acids

24
Q

the loop of henle extends from ____ to ______

A

proximal to distal convoluted tubules

25
Q

thick segments of henle limbs

A

simple low cuboidal epi

no brush border

26
Q

thin segments of henle limbs

A

simple squame

27
Q

functions of descending limb of henle

A

permeable to water, Na, Cl

28
Q

functions of ascending limb of henle

A

impermeable to water

actively reabsorb Cl, Na slowly follows

29
Q

what is the major function of the loop of henle

A

establish counter-current exchange system to create osmotic conditions to move water when ADH is present

30
Q

distal convoluted tubule and water

A

impermeable to water unless ADH is present

31
Q

what 2 specialized cells are present in the collecting duct

A

principal cells

intercalated cells

32
Q

principal cells

A

reabsorb Na and water

secrete K actively

33
Q

intercalated cells

A

secrete H+ or bicarbonate ions

34
Q

list the excretory passages

A

renal pelvis
ureter
bladder

35
Q

list the layers of excretory passages

A

mucosa
submucosa
Muscularis
adventitia

36
Q

describe the mucosa layer of excretory passageways

A

transitional epi

few smooth muscle cells

37
Q

describe the Muscularis layer of excretory passageways

A

inner longitudinal

outer circular smooth muscle coating ureter

38
Q

layers of smooth muscle in urinary bladder for the _____ muscle

A

detrusor muscle

39
Q

types of glands found in the male ureter

A

lacunae of Morgagni

glands of littre