L20: Integument Flashcards
list layers from epidermis to hypodermis
epidermis BM dermis subcutaneous fat superficial fascia hypodermis
list the layers of the epidermis
stratum basale spinosum granulosum lucidum corneum cornified cell envelope
the germinativum is another name for ?
stratum basale
stratum basale
deepest layer
single layer of cells held together by desmosomes
hemidesmosomes hold to the basal lamina
location of stem cells
stratum spinosum
prickle cell layer
keratin present
lamellar bodies
tonofibrils
lamellar bodies
membrane coating granules
tonofibrils
form intercellular bridges
stratum granulosum
granular cell layer
multilayered - flattened nucleated keratinocytes
lamellar bodies
tonofilaments
stratum lucidum
absent in thin skin
flat keratinocytes - no nuclei or organelles present
contains eleiden
stratum corneum
most superficial
multilayered 5 -50
fully keratinized
describe keratinization
entire cell is filled w/ keratin
keratin cross linking w/ filaggrin
cornified cell envelope
extracell - multi lamellar lipid layer
intracell - involucrine and fillagrin
involucrine
small proline-rich proteins
filaggrin
cross link keratin
describe the 2 layers of the dermis
- papillary layer - loose elastic CT - separated from epidermis by basal lamina
abundant capillaries - reticular layer - dense irregular CT w/ cells
cells of the reticular dermis layer
fibrocytes
macrophages
adipocytes