L20: Integument Flashcards

1
Q

list layers from epidermis to hypodermis

A
epidermis
BM
dermis
subcutaneous fat
superficial fascia
hypodermis
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2
Q

list the layers of the epidermis

A
stratum basale
spinosum
granulosum
lucidum
corneum
cornified cell envelope
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3
Q

the germinativum is another name for ?

A

stratum basale

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4
Q

stratum basale

A

deepest layer
single layer of cells held together by desmosomes

hemidesmosomes hold to the basal lamina
location of stem cells

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5
Q

stratum spinosum

A

prickle cell layer
keratin present
lamellar bodies
tonofibrils

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6
Q

lamellar bodies

A

membrane coating granules

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7
Q

tonofibrils

A

form intercellular bridges

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8
Q

stratum granulosum

A

granular cell layer
multilayered - flattened nucleated keratinocytes
lamellar bodies
tonofilaments

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9
Q

stratum lucidum

A

absent in thin skin
flat keratinocytes - no nuclei or organelles present
contains eleiden

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10
Q

stratum corneum

A

most superficial
multilayered 5 -50
fully keratinized

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11
Q

describe keratinization

A

entire cell is filled w/ keratin

keratin cross linking w/ filaggrin

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12
Q

cornified cell envelope

A

extracell - multi lamellar lipid layer

intracell - involucrine and fillagrin

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13
Q

involucrine

A

small proline-rich proteins

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14
Q

filaggrin

A

cross link keratin

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15
Q

describe the 2 layers of the dermis

A
  1. papillary layer - loose elastic CT - separated from epidermis by basal lamina
    abundant capillaries
  2. reticular layer - dense irregular CT w/ cells
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16
Q

cells of the reticular dermis layer

A

fibrocytes
macrophages
adipocytes

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17
Q

characteristics of the hypodermis

A
loose CT
underlying the dermis
= superficial fascia
not apart of skin
may contain fat cells
18
Q

location of thick skin vs. thin skin

A

thick = palms and soles of feet - hairless

everything else = thin skin

19
Q

primary dermal ridges are used for

A

finger printing

are found every where except forehead, ear, perineum and scrotum

divide into 2 secondary dermal ridges

20
Q

interpapillary peg

A

downward growth of epidermis along crests

21
Q

secondary dermal ridges

A

occur in double rows and branches

thin collagenous, reticular and elastic fibers

22
Q

dermal papillae

A

upward projection from each secondary dermal ridge

23
Q

epidermal permeability barrier

A

lipids covalently linked to involucrine between cells

water tight barrier

24
Q

tight junctions in the ______ contribute to ?

A

granulosum

water tight barrier

25
Q

Langerhans cells

A

= dendritic cells

primarily found in spinosum - migrating from epidermis to lymph nodes

contain birbeck granules

26
Q

merkel cells

A

mechanoreceptors
germinativum
contain catecholamine-like granules

27
Q

melanocytes

A

do not form desmosome attchments in epidermis

inject melanin granules into keratinocytes

28
Q

embryonic origins of the epidermis and dermis

A

ectoderm

dermis - mesoderm

29
Q

sebaceous glands are _____ glands - meaning they will die w/ their secretions

A

holocrine

are associated w/ a hair follicle into which they release they secretions

30
Q

sebaceous glands are found everywhere in the epidermis except

A

palms and soles

31
Q

sudoriferous glands are also known as

A

sweat glands

can be merocrine or apocrine

32
Q

merocrine - sudoriferous glands

A

coiled, simple tubular secretory portions w/ myoepithelial cells

33
Q

where are apocrine sudoriferous glands found

A

labia majora
areola
axillary
anal regions

34
Q

special types of sudoriferous apocrine glands

A

ceruminous glands - ear wax

glands of moll

35
Q

components of hair follicles

A

external root sheath
internal root sheath
hair shaft
hair bulb

36
Q

list sensory receptors in the skin

A

Meissner’s corpuscle

pacini corpuscle

37
Q

external root sheath of hair vs. internal root sheath

A

ext - down growth of epidermis

in - generated by bulb matrix

38
Q

layers of the internal root sheath

A

Henle’s layer - outmost

Huxley’s layer

cuticle

39
Q

hair shafts

A

innermost medulla

outer cortex

cuticle

40
Q

hair bulb

A

expanded lower part of follicle
matrix
vascularized dermal papilla