L214/215

Question 1

Dentist who game first successful demonstration of ether anesthesia

Answer 1

William Thomas Green Morton

Question 2

MAC

Answer 2

Minimum alveolar concentration: Concentration at which 50 percent of patients do not respond to stimulus

Question 3

Nitrous oxide guy who committed suicide

Answer 3

Horace Wells

Question 4

Meyer-Overton correlation

Answer 4

Anesthesia begins when anesthetic reaches critical concentration in membrane lipids (high correlation with solubility in olive oil)

Question 5

Good targets for anesthetics

Answer 5

ligand gate ion channels

GABA recepotrs

Question 6

Competition between anesthetics and action potentials

Answer 6

Synaptic transmission more sensitive to anesthetics

Question 7

Structures important for consciousness

Answer 7

Reticular activating formation

Thalamic loop

Question 8

Structures important for memory

Answer 8

Limbic system

Question 9

Stages of anesthesia

Answer 9

Analgesic (induction)
Excitement
Surgical anesthesia
Medullary paralysis (bad)

Question 10

Low blood:gas coefficient vs

High blood:gas coefficient

Answer 10

Low: faster induction and recovery
High: Slower induction and recovery

Question 11

Nitrous oxide properties

Answer 11

Low solubility
High MAC
Fast onset, fast recovery

Question 12

Barbiturate mechanism of action

Answer 12

Potential GABA-A receptors

Question 13

Barbituate times
Ultra short
Short
Intermediate 
Long

Answer 13

Ultra-short 15-30 minutes
Short 2-4 hours
Intermediate 4-6 hours
Long 6-8 hours

Question 14

Benefits of IV barbituates

Answer 14

Rapid distribution
Reduced cardiac depression
No risk of malignant hyperthermia
Eliminate occupational risk of volatile

Question 15

Methoxhexital

How fast, duration

Answer 15

Very fast, short duration

5-7 minutes

Question 16

Ketamine produces

Answer 16

Dissociative anesthesia