L20 Flashcards
what is the major fueling pathway for our exercising
skeletal muscles
Oxidative
phosphorylation
when do we use oxidative phosphorylation
when we excersize over 2 min
We need to get O2 to the muscles which diffused into the blood in the lungs then it goes to the mussels where CO2 is produced and then that cose back to the lungs where it is expelled. For all of this to happen we need…. what
a healthy respiratory system
3 main goals of respiratory
system during exercise
Ensure that partial pressure of O2 (PaO2) in our arteries is well
maintained to allow adequate O2 supply to exercising muscles
To eliminate metabolic and nonmetabolic CO2 to maintain the partial pressure of CO2 (PaCO2)
in our arteries
To assist in the buffering of
metabolic acids produced
during high intensity exercise
at sea level what is the PP of O2
159 mmHg
at sea level the PP of O2 = 159mmHg, what is it when it reaches the alveoli
105mmHg
what is the process in which O2 is consumed by the muscles
oxidative poshorilation
at rest what % of O2 do we use (because of oxidative phosporilation)
This drops the conc of O2 down from 100 to 40 therefore at resu we use about 60 of O2
at rest how many mL of O2 do you have per 100mL of blood
20 mL
at rest how many mL of O2 will the muscles extract from the blood
4-5mL
when we are excersizing this chages
what are the sources of CO2
Metabolic (oxidative phosporilasiatin)
• Glucose + 6O2 → 30 ATP
+ 6CO2 +6H2O
• Palmitate (FFA) + 23O2 → 108ATP + 16 CO2
Non-metabolic
• H+ + HCO3 → H2CO3 →
CO2 + H2O
H+ ions get buffered by bicarbonate which is in the muscles but when H+ binds it produces CO2
what is tidal volume
definition and velue
Tidal volume is the amount of air breathed in with each normal breath. The average tidal volume is 0.5 litres (500 ml).
how do you increase ventilation
(1) Increase tidal volume
(2) Increase breathing frequency
what is the relative increse in ventilation rate, tidal volume and breathing frequency that occurs because of excersize
VE = 32x
VT = 8x
f = 4x
The increase in ventilation during exercise
is controlled by what
both neural and humoral
(chemical) pathways.