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BMSC 240 > L19 > Flashcards

L19 Flashcards

1
Q

How are plasma cells or memory B-cells formed

A

when native b-cells are activated upon antigen exposure.

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2
Q

Agglutination

A

reduces number of infection units to be dealt with

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3
Q

Opsonization

A

coating antigen with antibody enhances phagocytosis

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4
Q

Neutralization

A

blocks adhesion of bacteria and viruses to mucosa

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5
Q

Activation of complement

A

causes inflammation and cell lysis

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6
Q

Antibody-dependent cell-mediated cytotoxicity

A

antibodies attached to target cell cause destruction by eoisinophils and NK cells

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7
Q

What are haptens

A

penicillin, urushiol, cocaine. sample (usually a protein) that contains polysaccharides, nucleic acids and even smaller molecules

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8
Q

What is the difference between polyclonal and monoclonal antibodies

A

POLY- natural immune reaction. several B-cells

MONO- single B-cells made immortal

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9
Q

How are monoclonal antibodies produced

A

the fusion of B-cells with cancerous B-cells to make them immortal to make hybridoma

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BMSC 240 (7 decks)

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