L15 & 16 - ANS 1 & 2 Flashcards
Allostasis
Maintaining balanced system with changing environment - can be predictive (e.g. pregnancy and lactation) or reactive
2 types of ganglia in sympathetic NS and 1 more worth mentioning
Paravertebral ganglia aka sympathetic chain, 2 chains of ganglia run next to vertebral column
Prevertebral ganglia aka mesenteric ganglia (single row of ganglia at midline)
Innervation of adrenal medulla to secrete hormones A and NA
In relation to airways, what does the sympathetic NS do
Relax and dilate airways
How is mass activation and coordination achieved in the sympathetic NS? Is it the same for the para NS?
1) Activation of adrenal medullary nerves
2) Activation of many preganglionic pathways at once
3) Some preganglionic neurons have many axon collaterals so can activate many postgrang. neurons at once
No, in para NS - no adrenal medullary and not as much axon collaterals and hence is limited.
PARA NS: Pregang. axons at two sites
Brainstem nuclei and sacral spinal cord (axons project via spinal nerves)
Sacral postgang. neurons of para NS lie in
Pelvic plexus (inf. hypogastric plexus) - also contain symp neurons that are unusually long and vulnerable to surgical injury
Synaptophysin
Synaptic protein found in terminals of preganglionic axons
SYMP NS - Which postganglionic neurons release ACh?
Neurons of sweat glands release acetylcholine for the activation of muscarinic receptors.
What is functional antagonism?
Opposing actions but via different cells/parts of muscle
e.g. Symp - contract pupil dilator muscle, contract base of bladder (ontinence)
Para - contract pupil sphincter muscle, contract body of bladder (voiding)
Effect of symp and para on salivary glands
Symp - serous secretion
Para - mucous secretion
Some tissues only have one type of innervation
Some tissues only have one type of innervation
Electroceuticals
Swapping drugs for devices, with the goal of activating or reducing neural pathway of choice
Miturition
Voiding
Dsyreflexia is a SPI in spinal region above
T6
External sphincter muscle of urethra - Vol or invol
Vol