L13: Beyond the 20th Century Flashcards
1
Q
Who was Selman Waksman and what was his contribution to medicine?
A
- He was a soil microbiologist who discovered Streptomyces griseus, the source of streptomycin used as the first anti-TB drug. He coined term antibiotics
1
Q
Who was Andreas Gruentzig and what was his contribution to medicine?
A
- He devised coronary balloon angioplasty
2
Q
Who was Alexander Fleming and what was his contribution to medicine?
A
- He was a bacteriologist in London who accidentally discovered that Penicilium mold were destructive to Gram positive bacteria.
3
Q
What is Salvarsan?
A
- Specific treatment for syphilis prepared and developed by Paul Ehrlich and Sahachiro Hata
4
Q
Who coined the term antibiotics?
A
- Antibiotics were first coined by Selman Waksman.
5
Q
Who was Gerhard Domagk and what was his contribution to medicine?
A
- He investigated azo dyes as antibacterials. - Found red dye, Prontosil, cured mice injected with lethal numbers of streptococci - Active component in drug was sulfanilamide, the first sulfa drug.
6
Q
Who was Paul Ehrlich and what was his contribution to medicine?
A
- He was a researcher with Sahachiro Hata who helped found modern chemotherapy. Developed Salvarsan (preparation 606) that was a specific treatment for 1909.
7
Q
Who was Werner Forssman and what was his contribution to medicine?
A
- He demonstrated safe cardiac cartheterization on himself in 1929, which lead to anatomic demonstration of coronary arteries and real-time physiologic recordings of cardiac function
9
Q
Who was Sahachiro Hata and what was his contribution to medicine?
A
- He was a researcher with Paul Ehrlich who helped found modern chemotherapy. Developed Salvarsan (preparation 606) that was a specific treatment for 1909
10
Q
Who was Howard Florey and what was his contribution to medicine?
A
- During his studies on antibacterial substances, he discovered Fleming’s research. He ended up isolating penicillin from Penicilium mold.
11
Q
What is Prontosil?
A
- It is a red dye discovered by Gerhard Domagk that cured mice of streptococci infection. It is the first sulfa drug.
