L12 Laminar and Turbulent flow Flashcards
How to work out Flow
Flow = pressure / resistance
from what pressures does the air or the blood flow to
from high pressure to low pressure
How to work out BP
Arterial blood pressure - cardiac venous pressure
how to work out CO
BP/ resistance (TPR)
what is the resistance in the CVRS
It’s the vascular resistance in the vascular beds (vessels)
work out Air flow ?
pressure gradient (batometric pressure - alveolar pressure)/ airway resistance - the pressure gradient needs to be bigger than the resistance so the air can flow during inspiration
During inspiration, what is the pressure gradient like so is it PB > PA or PA
PB > PA
-this allows the air to flow inside
during Expiration, what is the pressure gradient like so is it PB > PA or PA
PA>PB
what is the resistance in the RS
in the airways of the lungs
is the resistance greater in CVS or RS?
- the resistance is greater in the CVS because there is a greater driving force generated in the CVS.
What is the formula for Poiseuille’s law
V dot = change in P x ((pi x r^4)/8nl)
- this formula only applies to laminar flow
what is flow proportional to
driving pressure so
- for RS, it’s PB-PA depending on the chest wall muscles
- for CVS, it’s ABP-CVP, depending on cardiac work
What is flow inversely proportional to
-resistance
so R = 8nl/pi x r^4
- viscosity(n) is constant, can be changed by heliox or haematocrit
- the length of the blood vessels set up by the anatomy so cant change it
- radius (r) is dependent on the smooth muscle so we have physiological control over it so like (bronchodilation/constriction for RS and vasodilation/constriction for CVS)
what is resistance inversely proportional to?
- R = 1/ r^4
- as the radius increases, the R will decrease
- radius (r) is dependent on the smooth muscle so we have physiological control over it so like (bronchodilation/constriction for RS and vasodilation/constriction for CVS)
what is laminar flow and describe the velocities of the flow
- It’s a flow where the centre of the flow has the max velocity
- the outermost layer of the flow nearest to the vessel wall is the fluid that is immobile
- after that, each successive layers from fluid layer to the centre, it increases in speed
- it has a parabolic flow pattern
What is LF inversely proportional to ?
- to R
- so it’s energy efficient and in order so it’s silent flow
What is turbulent flow (TF)
- it’s a random flow where tje parabolic pattern is lost
-the fluid and blood mixes so it’s noisy
-less energy effecient because we lose KE
so the energy is lost of sound
What is TF inervsely proportional to
square root of chnage in pressure
What factor can determine whether it’s TF or LF
Reynolds number (NR) - NR =( density x diameter x velocity ) / viscosity
What factors can increase occurrence of TF
- density
- diameter of the tube
- velocity of the flow
What factor can decrease the TF
- viscosity
- so if the viscosity is higher, the TF occurs less often
- Where does TF occur in the RS and why?
- in the trachea
- because there is a higher velocity and large radius, contributing to an increase of NR
- Energy is lost so the flow is no longer proportional to change in Pressure
- but the flow is now proportional to square root of change in Pressure
what flow occurs in the bronchial tree
- both TF and LF
What flow occurs in small airways
LF
Where does LF occur in the CVRS
- most blood vessels where the RBCs would be at the centre of the vessel at the max velocity
Where does TF occur in CVS
in the vessels where there is an irregularity so like valves, clots, blood vessel branches
Why does narrowing of blood vessels lead to increases flow velocity
Velocity = Flow/ CSA
so if the CSA decreases, the velocity increases
normal Indicators for TF
- herat sounds caused by closing of the AV and SLV
-
What is a murmur caused by the TF
- it’s when the area of the vessel is smaller than usual like the valves are fused together
- this leads to higher velocity because it needs to compensate for the same flow
- causing more TF than usual
How can a cuff measures the systolic and diastolic pressure ?
- when the cuff is first used, it stops the flow because it is tight
- but as the cuff is gradually released, it produces sounds as the flow becomes turbulent due to the tightening of the cuff
- so the systolic pressure is when the korotkoff sounds start happening and diastolic pressure is when it stops
- after wards, the cuff becomes loose and the flow becomes laminar soon after