Krebs cycle

Question 1

When is aerobic glycolysis seen?

Answer 1

in invasive cancers

Question 2

What does aerobic glycolysis do?

Answer 2

converts glucose into lactic acid in the presence of oxygen

Question 3

Why do cancer cells use aerobic glycolysis?

Answer 3

because running fast glycolysis creates intra-and pericellular acidic conditions, which tumor cells proliferate in. Normal cells cannot adapt to acidic conditions

Question 4

What kind of cells do end stage metastases favor?

Answer 4

glycolytic cells and cells resistant to hypoxia

Question 5

Are early tumors vascular?

Answer 5

Not before breaching the basement membrane. It can tolerate anaerobic conditions

Question 6

What occurs during the aerobic metabolism of a carb?

Answer 6

electrons are taken from carbohydrates and given to oxygen in the electron transport system

Question 7

What occurs during fermentation of a carbohydrate?

Answer 7

electrons are taken from carbohydrates and given back while making ATP. This is anaerobic and the products are 2 lactate and 2 ethanol