KREB'S CYCLE Flashcards
the central pathway of all metabolic processes
CITRIC ACID CYCLE
-sequence of reactions in the mitochondria that oxidizes the acetyl moiety of Acetyl-CoA to Carbon Dioxide
CITRIC ACID CYCLE
-reduces coenzymes that are reoxidized through the electron transport chain linked to the formation of ATP
CITRIC ACID CYCLE
the cycle start with the reaction between the acetyl moiety of Acetyl-CoA and the 4 Carbon dicarboxylic acid oxaloacetate, forming six-carbon tricarboxylic acid called
CITRATE
enzyme that catalyzes the reaction of oxaloacetate (4 carbon dicarboxylic acid) and Acetyl-CoA to form Citrate (6 carbon tricarboxylic acid)
Citrate Synthase
two sub-steps that occur during isomerization of citrate
DEHYDRATION, REHYDRATION
enzyme that catalyzes the isomerization of citrate
ACONITASE
H2O being a neutral compound is necessary to ________ of citrate forming it to Cis-Aconitate
RETAIN STABILITY
enzyme that catalyzes the dehydrogenation of isocitrate
ISOCITRATE DEHYDROGENASE
coenzymes involved in the dehydrogenation of isocitrate
MG or MN IONS
Isocitrate undergoes dehydration to initially form what
OXALOSUCCINATE
isocitrate undergoes decarboxylation to
a-ketoglutarate
enzyme involved in the oxidative decarboxylation of A-KETOGLUTARATE to form SUCCINYL-COA
A-KETOGLUTARATE DEHYDROGENASE
cofactors involved in the oxidative decarboxylation of A-KETOGLUTARATE to form SUCCINYL-COA
Thiamine Diphosphate, Lipoate, NAD+, FAD, and CoA
Succinyl-CoA is converted to
SUCCINATE