GLUCONEOGENESIS

Question 1

-formation of glucose from non-sugars

the process of synthesizing glucose from noncarbohydrate precursors

Answer 1

GLUCONEOGENESIS

Question 2

major substances in GLUCONEOGENESIS

Answer 2

1. Glucogenic Amino Acids
2. Lactate
3. Glycerol
4. Propionate

Question 3

results from a failure to perform gluconeogenesis due to liver or kidney damage

Answer 3

HYPOGLYCEMIA

Question 4

results from excessive gluconeogenic activity of critically ill patients in response to injury and infection

Answer 4

HYPERGLYCEMIA

Question 5

enzyme involved when pyruvate is carboxylized to phosphoenolpyruvate which is an ATP-requiring reaction with the vitamin Biotin as a coenzyme.

Answer 5

PYRUVATE CARBOXYLASE

Question 6

catalyzes the decarboxylation and phosphorylation of oxaloacetate to phosphoenolpyruvate using GTP as the phosphate donor

Answer 6

PHOSPHOENOLPYRUVATE CARBOXYKINASE

Question 7

determines whether if a tissue is capable of synthesizing glucose (or glycogen) not only from pyruvate but also from triose phosphates

Answer 7

F-6-P

Question 8

prevents muscles to export glucose in the bloodstream

Answer 8

G-6-P

enzyme: Glucose-6-phosphatase

Question 9

• major precursor of glucose ruminants

- enters gluconeogenesis via the CAC

Answer 9

PROPIONATE

Question 10

Propionyl-CoA is carboxylated to D- Methylmalonyl-CoA by the enzyme

Answer 10

PROPIONYL-COA CARBOXYLASE (biotin dependent enzyme)

Question 11

D-MM-COA is converted to L-MM-COA by

Answer 11

D-MM-COA RASEMASE

Question 12

L-MM-COA is converted to SUCCINYL-COA by

Answer 12

METHYLMALONYL-COA MUTASE

Question 13

chronological sequence of the conversion of Propionate to enter the CAC

Answer 13

Propionate, Propionyl CoA, DMMCoA, LMMCoA, Succinyl CoA