Klinisk hæmatologi og immunologi Flashcards

0
Q

Hvad er 2. grads hæmostase?

A

Koagulation

Fibrin formation

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1
Q

Hvad er 1. grads hæmostase?

A

Karkonstriktion

Blodpladeaktivering og plug formation

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2
Q

Hvordan lokaliseres genereliseret blødning til enten 1. grads koagulationsfejl eller 2. grads?

A

ekkymoser, pettechier, hæmaturi, melæna : 1.grads (karvæg, blodplader)

Hæmatom, Hæmarthron, Hæmothorax, hæmoabdomen: 2. grads (koagulationsfaktorer)

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3
Q

Hvad er fremgangsmåden for diagnostik af patient mistænkt for sygdom i blodplader/kar?

A

Blodpladecount.

Trombocytopeni: 
- destruktion (IMT)
- Nedsat produktion (KM)
- Øget forbrug (DIC)
Sequestration (milt)

Ingen thrombocytopeni:

  • Øget blødningstid
    • thrombopati
      - Vaskulært problem
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4
Q

Hvad betyder ACT?

A

Activated Clotting Time

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5
Q

Hvad er normal ACT i hunde.?

A

75 - 120 sek

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6
Q

Hvad er normal ACT i katte?

A

under 80 sekunder

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7
Q

Hvad består en Point of Care koagulationsprofil af (POC)?

A
Platelet number
Buccal mucosa bleeding time (BMBT)
ACT 
POC APTT & PT
D-dimer
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8
Q

Hvad er APTT?

A

Activated Partiel Thromboplastin Time

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9
Q

Hvad er D-dimer?

A

Et nedbrydningsprodukt af fibrin

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10
Q

Har danske schæfere ofte hæmofili A?

A

Nej, populationen er nu fri for hæmofili A, grundet avl

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