kidney pics Flashcards

1
Q

where is this?

A

cortex

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2
Q

which is distal which is proximal?

where is this?

can the glomerulus be idetified?

A

proximal = filled with pink

distal = empty center

its in the cortex;

yes it can be identifies

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3
Q

what does the thin limb do?

what does the thick limb do?

what are their respective epithelium?

A

pulls water from the filtrate (concentrates urine)

the thick pumps ions out to decrease osmolarity

thick= cuboidal

thin=squamous

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4
Q

what is in this picture?

A

podocyte and its pedicle (arrow)

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5
Q

what do mesagial cells do?

A

engulf any protein accumulated on the capillary

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6
Q

how are endothelial cells in the kidney?

A

fenestrated with pedicles of podocytes

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7
Q

what does the proximal tubule do?

A

helps with reabsorption of glucose and sodium using microvilli

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8
Q

what does the distal tubule do?

when do they do their function?

A

Na and K retention

they work in presence of aldosterone

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9
Q

what does the collecting tube do? what happens if there is ADH?

A

it collects all the filtrate and if there is ADH it will lose some of its water

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10
Q

where is the macula densa? what epithelium they have?

A

in front of the afferent arteriole

they have columnar cells

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11
Q

what is this?

A

thin limb

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12
Q

where is this?

what are the T, CD, and the cells that have almost like a star in their center?

A

medulla

t = thin limb

star = thick limb

CD= collecting duct

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13
Q

how permeable is the collecting duct to water?

A

very impermeable

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14
Q

where do we acidify our urine?

A

collecting duct

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15
Q

what are the dark cells

and light cells?

A

dark = secretion of bicarbonate and protons

light = measures flow (ADH regulated aquaporin2 water channels)

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16
Q

what is a and b?

A

a = dark cells

b = light cell

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17
Q

what does the macula densa do?

A

measure flow

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18
Q

what do JGlomerular cells do?

A

they increase flow of filtrate releasing renin

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19
Q

explain the renin-angiotensin cascade?

A

low filtrate recognized by macula densa

JG cells secrete renin

renin gets to liver

liver cleaves angiotensinogen/produces angiontensin I

angiotensin I goes to lungs

angiotensin converting enzymes convert Angio I to Angio II

Angio II causes increase in blood volume

20
Q

do distal or proximal tubules have microvilli?

A

distal no

proximal yes

21
Q

who helps the macula densa and JG cells communicate?

A

mesagial cells

22
Q

what is this?

A

macula densa

23
Q

where is the concentration of urea, sodium and chloride higher in the medulla?

A

ther further down you go into the medulla

24
Q

the ascending thick limb pull what out and what follows?

A

pulls Cl out and Na follows

25
is the descending thin limb permeable to water?
yes, it pulls water out
26
through were does the urea enter?
through the ascending thin limb
27
the ureters have what epithelium?
transitional
28
where is this?
ureter
29
where is this?
ureter
30
where is this?
ureter
31
where is this?
ureter
32
what does the ureterovesicular junction do?
prevents urine backflow
33
where is this?
bladder
34
what is this?
baldder
35
where is this?
bladder
36
what epithelium is the urethra
stratified squamous
37
where is this?
urethra
38
what are these?
bulbous cavernosum and spongiosum
39
what is alport syndrome?
defect in tye 4 collagen
40
what is goodpastures?
autoimmune response to attack the glomerular basement membrane
41
what is IgA nephropathy?
IgA accumulates in kidney causing to leak blood (youll see blood in urine)
42
wha tis interstitial nephritis?
the spaces between the kidney tubules get swollen related to nsaids and diuretics
43
what is chronic kidney disease?
high levels on creatinine causing failure of glomerular filtration
44
what are kidney stones?
crystal aggregation on the kidneys
45
in diabetes there is decrease of what hormone that interacts in the kidney?
ADH you have polyurea
46
what happens in diabetes mellitus?
insulin spills in urine