Key Associations part 1 Flashcards
Mitochondrial inheritance
Disease occurs in both males and females, inherited through females only
Intellectual disability
Down syndrome, fragile X syndrome
Vitamin deficiency (USA)
Folate (pregnant women are at high risk; body stores only
3- to 4-month supply; prevents neural tube defects)
Lysosomal storage disease
Gaucher disease
Bacterial meningitis (> 6 months old)
S pneumoniae
Bacterial meningitis (newborns and kids)
Group B streptococcus/E coli/Listeria monocytogenes (newborns)
HLA-DR3
Diabetes mellitus type 1, SLE, Graves disease, Hashimoto thyroiditis (also associated with HLA-DR5), Addison disease
HLA-DR4
Diabetes mellitus type 1, rheumatoid arthritis, Addison disease
Bacteria associated with gastritis, peptic ulcer disease, and gastric malignancies (eg, adenocarcinoma, MALToma)
H pylori
Opportunistic respiratory infection in AIDS
Pneumocystis jirovecii pneumonia
Helminth infection (US)
Enterobius vermicularis
Viral encephalitis affecting temporal lobe
HSV-1
Infection 2° to blood transfusion
Hepatitis C
Food poisoning (exotoxin mediated)
S aureus, B cereus
Osteomyelitis
S aureus (most common overall)