Kahoots Flashcards
What describes the study of how drugs move through the body?
Pharmokinetics
Which of the following drugs is a strong inducer?
a) Grapefruit
b) Amiodarone
c) Azithromycin
d) Carbamazepine
d) Carbamazepine
True or false: Takes abt 10 half lives to reach a steady state
False
CYP P450 enzymes are mostly located where?
Liver
Most phase II trials are ___________ and have __________ patients
RTCs; 100-300
Codeine is a prodrug that gets metabolized (by CYP 4D6) into what?
Morphine
Which is the most common CYP in adults?
CYP P3A4
True or false: Warfarin has a low volume of distribution because it’s bound to keratin in the plasma
False; bound to albumin (protein)
Diphenhydramine causes dry mouth via _____________ activity at the ______________ receptor
antagonist; muscarinic