K shifts Flashcards
Hypo-osmolality
K shift INTO cell (causing HYPOkalemia)
Alkalosis
K shift INTO cell (causing HYPOkalemia)
beta-adrenergic agonist (incr. Na/K ATPase)
K shift INTO cell (causing HYPOkalemia)
Insulin (incr. Na/K ATPase)
K shift INTO cell (causing HYPOkalemia)
Digitalis (block Na/K ATPase)
K shift OUT cell (causing HYPERkalemia)
Hyper-osmolality
K shift OUT cell (causing HYPERkalemia)
Lysis of cells (crush injury, rhabdomyolysis, tumor lysis syndrome)
K shift OUT cell (causing HYPERkalemia)
Acidosis
K shift OUT cell (causing HYPERkalemia)
beta-blocker
K shift OUT cell (causing HYPERkalemia)
High blood sugar (insulin deficiency)
K shift OUT cell (causing HYPERkalemia)
Succinylcholine (incr. risk in burns/muscle trauma)
K shift OUT cell (causing HYPERkalemia)
What substance responds to hyperkalemia?
Aldosterone. Increase K excretion