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1 STEP UW Nephrology > Beta blockers on RAAS > Flashcards

Beta blockers on RAAS Flashcards

1
Q

Regulation of the RAAS involves 3 components?

A
  1. Macula densa (distal tubule sodium sensor)
  2. Intrarenal baroreceptors
  3. Beta-adrenergic receptors.
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2
Q

Beta-adrenergic receptors in RAAS, what type?

A

Beta 1 receptors.

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3
Q

Beta-adrenergic receptors location in kidney?

A

juxtaglomerular cells, which stimulates release of renin.

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4
Q

Effect of beta-1 blockers on RAAS?

A

inhibits release of renin

therefore –> reduced Angiotensinogen conversion to ATI –> decr ATII and aldosterone

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5
Q

Why beta blockers do not have effect on bradykinin?

A

Have no effect on ACE activity

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1 STEP UW Nephrology (14 decks)

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